Bus Tickets from St. Louis to Boston, MA, US

Next departures

Next departures for St. Louis to Boston on November 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Gateway Station
    		Boston (South Station)Cheapest
    Greyhound Lines, Inc.
      		Gateway Station
      		Boston (South Station)Fastest
      Greyhound Lines, Inc.
        		Gateway Station
        		Boston (South Station)No tags
        Greyhound Lines, Inc. + FlixBus
          		Gateway Station
          		BrooklineNo tags

          Last refresh of the prices: Last Thursday at 3:22 PM CDT.

          Accepted payments

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          • China Union Pay
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          • JCB payment
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          Compare 2 ways to go from St. Louis to Boston

          We recommend taking the bus

          Among the sustainable travel choices, the bus stands out as a good way to reach Boston. The journey takes about 1 day, 10 hours 45 minutes, and with fares starting at just US$117, it presents an excellent value for a comfortable ride.

          7bus per day
          1d 10hAverage Duration
          1662 kmDistance
          42kgCO₂ emissions
          Bus
          		Average PriceUS$117 - US$349Average Duration1d 10h
          42kg CO₂e
          Train
          		Average PriceUS$303 - US$2,339Average Duration1d 14h
          151kg CO₂e

          Bus St. Louis to Boston, MA, US: Trip Overview

          Average Ticket PriceUS$196
          Average Bus Trip Duration1d 10h
          Number of daily buses7
          Earliest bus departure1:00am
          Distance1662 km
          Latest bus departure11:30pm

          St. Louis to Boston Bus

          Busbud helps you find a bus from St. Louis to Boston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

          We make it our job to connect you with the most dependable bus companies that cover bus service from St. Louis to Boston.

          From cheap bus tickets to more luxurious buses travelling from St. Louis to Boston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

          Frequently asked questions on the trip St. Louis - Boston, MA, US

          1. What is the travel distance from St. Louis to Boston?

            The distance between St. Louis and Boston is approximately 1669 km (1035 miles).

          2. What are the departure and arrival locations for buses traveling from St. Louis to Boston?

            Buses departing from Gateway Station in St. Louis will take you to Back Bay Station in Boston.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          10-31
          US$110
          11-01
          No data
          Today
          No data
          11-03
          No data
          11-04
          US$125
          11-05
          No data
          11-06
          No data
          11-07
          No data
          busbud logoThe cheapest trip from St. Louis to Boston, MA, US was searched and found on Oct 31, 2025 with a price of US$110

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Boston, MA, US, as early as possible.

          You can expect to pay from US$110 to US$128 for a bus ticket from St. Louis to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$125 which is on 2025-11-04.

          About Bus Travel

          Bus Travel Tips

          Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between St. Louis and Boston!

          From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from St. Louis to Boston.

          Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Boston that are otherwise impossible to come by with a plane.

          Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from St. Louis to Boston.

          Did you know?

          Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

          One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

          The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

          What's the cheapest way to go from St. Louis to Boston, MA, US?

          busbud logoThe bus is the cheapest travel choice for this destination

          Will you be returning to St. Louis by bus?

          Bus from Boston, MA, US to St. Louis

          You can also go to Boston, MA, US by train

          Train from St. Louis to Boston, MA, US

          Why choose Busbud?

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