Bus Tickets from St. Louis to Indianapolis

Next departures

Next departures for St. Louis to Indianapolis on October 13
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Gateway Station
Indianapolis Bus StationCheapest
Greyhound Lines, Inc.
Gateway Station
Indianapolis Bus StationFastest
Greyhound Lines, Inc.
Gateway Station
Indianapolis Bus StationNo tags

Last refresh of the prices: Today at 3:00 PM CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from St. Louis to Indianapolis

Bus
Average PriceUS$40 - US$138Average Duration4h 25m
9kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$70 - US$139Average Duration14h 39m
34kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St. Louis to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 4 hours 25 minutes, and with fares starting at just US$40, it presents an excellent value for a comfortable ride.

3bus per day
4h 25mAverage Duration
US$40Cheapest ticket
9kgCO₂ emissions

Bus St. Louis to Indianapolis: Trip Overview

Average Ticket PriceUS$42
Average Bus Trip Duration4h 25m
Number of daily buses3
Earliest bus departure2:00am
Distance371 km
Latest bus departure11:30pm

St. Louis to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from St. Louis to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from St. Louis to Indianapolis will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from St. Louis to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St. Louis - Indianapolis

  1. How far is St. Louis from Indianapolis?

    The distance between St. Louis and Indianapolis is around 371 km (230 miles).

  2. What are the departure and arrival locations for buses traveling from St. Louis to Indianapolis?

    Buses traveling this route start their trip at Gateway Station, in St. Louis, and end it at Greyhound Amtrak Station, in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-10
US$133
10-11
US$50
Today
US$126
10-13
US$51
10-14
US$37
10-15
US$34
10-16
US$34
10-17
US$34
busbud logoThe cheapest trip from St. Louis to Indianapolis was searched and found on Oct 15, 2025 with a price of US$34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Indianapolis, as early as possible.

You can expect to pay from US$34 to US$134 for a bus ticket from St. Louis to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$34 which is on 2025-10-15.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from St. Louis to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from St. Louis to Indianapolis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St. Louis to Indianapolis that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St. Louis to Indianapolis, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from St. Louis to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St. Louis by bus?

Bus from Indianapolis to St. Louis

You can also go to Indianapolis by train

Train from St. Louis to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis