Bus Tickets from Syracuse, US to Charleston (SC), US

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TodayJun 6
TomorrowJun 7
SunJun 8
MonJun 9
TueJun 10
WedJun 11
from US$171
ThuJun 12
from US$171
FriJun 13
from US$180

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 11 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: June 12 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 11 at
    Departure city: Syracuse
    Departure location: Syracuse (Regional Transportation Center)
    Arrival time: June 12 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 10:32 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Syracuse to Charleston

Bus
Average PriceUS$156 - US$207Average Duration1d 10h
30kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$200 - US$385Average Duration21h 42m
108kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Syracuse to Charleston

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 21 hours 42 minutes, and with fares starting at just US$200, it presents an excellent value for a comfortable ride.

1train per day
21h 42mAverage Duration
US$200Cheapest ticket
108kgCO₂ emissions

Bus Syracuse to Charleston: Trip Overview

Average Ticket PriceUS$157
Average Bus Trip Duration1d 10h
Number of daily buses3
Earliest bus departure3:00am
Distance1183 km
Latest bus departure9:00pm

Syracuse to Charleston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Syracuse to Charleston.

We make sure you can find a bus service from Syracuse to Charleston from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Charleston from Syracuse, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Syracuse, US - Charleston (SC), US

  1. How long does it take to get to Charleston from Syracuse by bus?

    The typical travel time from Syracuse to Charleston by bus is around 1d 10h. For the shortest travel time, select the fastest bus available, which will take you to Charleston in about 23h 5m.

  2. What is the distance between Syracuse and Charleston?

    The distance covered from Syracuse to Charleston is 1190 km (738 miles).

  3. What are the departure and arrival locations for buses traveling from Syracuse to Charleston?

    Buses traveling this route start their trip at Syracuse Airport, in Syracuse, and end it at Charleston Bus Station, in Charleston.

  4. What is the cheapest way to go from Syracuse to Charleston?

    The least expensive way to go from Syracuse to Charleston would be going by bus. With a starting ticket price of US$156, this bus becomes your top pick for this journey.

  5. How much is the bus from Syracuse to Charleston?

    The bus fare from Syracuse to Charleston is approximately US$157.

  6. Is it possible to travel by overnight bus from Syracuse to Charleston?

    Yes! Catch buses leaving from Syracuse until 9:00pm and reaching Charleston on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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06-11
US$182
busbud logoThe cheapest trip from Syracuse to Charleston was searched and found on Jun 11, 2025 with a price of US$182

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Charleston, as early as possible.

You can expect to pay from US$182 to US$182 for a bus ticket from Syracuse to Charleston based on the last 2 days. You can expect to find the cheapest price for the trip at US$182 which is on 2025-06-11.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Syracuse to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to Charleston, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Syracuse to Charleston.

Tune out to the fine sounds of your best music playlist on your bus trip from Syracuse to Charleston while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Syracuse to Charleston?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse by bus?

Bus from Syracuse to Charleston

You can also go to Charleston by train

Train from Syracuse to Charleston

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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