Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Syracuse (Regional Transportation Center) | Durham Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Syracuse (Regional Transportation Center) | Durham Greyhound Bus Station | No tags | ||||
| Bus | Syracuse (Regional Transportation Center) | Durham Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Syracuse (Regional Transportation Center) | Durham Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Syracuse (Regional Transportation Center) | Durham Greyhound Bus Station | No tags |
Get from Syracuse to Durham
The journey takes about 18 hours 55 minutes, and with fares starting at just $190, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Durham?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Durham
- A515 W Pettigrew St , Durham, NC 27703
- B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA - C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA - D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA
Compare bus companies
Frequently asked questions about travelling from Syracuse, US to Durham, NC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Durham?
The cheapest bus tickets from Syracuse to Durham start from $190. The average price for this route is around $256. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Durham?
The average bus travel time from Syracuse to Durham is 18h 55m, covering a distance of 822 km. The quickest bus can get you there in 17h 5m and is operated by FlixBus.
Which bus companies service the Syracuse to Durham route?
What are the earliest and latest departure times for the bus from Syracuse to Durham?
The earliest bus departs from Syracuse to Durham at 1:15am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Durham?
A bus trip from Syracuse to Durham generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to Durham?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Syracuse to Durham?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Syracuse to Durham?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Durham?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Durham, NC, US was searched and found on Dec 13, 2025 with a price of $221To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Durham, NC, US, as early as possible.
