What is the distance between Syracuse and Durham?

Syracuse and Durham are 509 miles (820 km) apart.

What are the departure and arrival stations when taking the bus from Syracuse to Durham?

If you're headed to Durham from Syracuse, chances are that your bus will depart from Regional Transportation Center and arrive at Durham Greyhound Bus Station. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Durham?

Once in Durham, you can start exploring the city and discover its surroundings. The top sights and things to do are Durham Castle, Crook Hall, Durham Cathedral, Oriental Museum and Killhope - The North of England Lead Mining Museum.

Bus Syracuse to Durham from $142 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Durham on November 6
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus		9:00pm	Syracuse (Regional Transportation Center)	17h 35m	2:35pm	Durham Greyhound Bus Station	CheapestFastest

Next departures for Syracuse to Durham on November 7
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	7:30am	Syracuse (Regional Transportation Center)	18h 55m	2:25am	Durham Greyhound Bus Station	Cheapest
	10:45am	Syracuse (Regional Transportation Center)	17h 5m	3:50am	Durham Greyhound Bus Station	Fastest
	3:00am	Syracuse (Regional Transportation Center)	19h	10:00pm	Durham Greyhound Bus Station	No tags
	3:55am	Syracuse (Regional Transportation Center)	21h 10m	1:05am	Durham Greyhound Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	9:00pm	Syracuse (Regional Transportation Center)	17h 35m	2:35pm	Durham Greyhound Bus Station	No tags

Last refresh of the prices: Yesterday at 5:21 PM EST.

Get from Syracuse to Durham

This route is served by bus only

The journey takes about 17 hours 40 minutes and with fares starting at just $66, it presents an excellent value for a comfortable ride.

6bus per day

17h 40mAverage Duration

510 milesDistance

21kgCO₂ emissions

Compare bus companies

FlixBus

3.5/511,207 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,355 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Syracuse and Durham?

Stops in Syracuse

A - Regional Transportation Center

B - Syracuse Airport

C - Syracuse University

D - Syracuse University - Lyman Hall

E - New York State Fairgrounds

F - Syracuse, NY

Stops in Durham

A - Durham Greyhound Bus Station

B - Compare Foods Durham

C - Durham Compare Foods Durham

D - Durham, NC

Frequently asked questions about traveling from Syracuse, US to Durham, NC, US by bus

What is the distance between Syracuse and Durham?
What are the departure and arrival stations when taking the bus from Syracuse to Durham?
What are the best sights and things to do in Durham?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/04

$144

11/05

No data

Today

$142

11/07

$159

11/08

No data

11/09

No data

11/10

No data

11/11

No data

The cheapest trip from Syracuse, US to Durham, NC, US was searched and found on Nov 6, 2025 with a price of $142

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Durham, NC, US, as early as possible.

You can expect to pay from $142 to $172 for a bus ticket from Syracuse, US to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $159 which is on 2025-11-07.

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.