Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Syracuse (Regional Transportation Center) | UCSD Health La Jolla Station | No tags | ||||
Greyhound + FlixBus | Bus | Syracuse (Regional Transportation Center) | Balboa Park | No tags | ||||
Greyhound + FlixBus | Bus | Syracuse (Regional Transportation Center) | San Diego (Old Town-FlixBus) | No tags | ||||
FlixBus + Greyhound | Bus | Syracuse (Regional Transportation Center) | Downtown SD (Seaport) | No tags | ||||
 | Bus | Syracuse (Regional Transportation Center) | Greyhound Bus Stop | No tags |
Get from Syracuse to San Diego
The journey takes about 3 days, 4 hours 15 minutes, and with fares starting at just $349, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and San Diego?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
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Frequently asked questions about travelling from Syracuse, US to San Diego, CA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to San Diego?
The cheapest bus tickets from Syracuse to San Diego start from $349. The average price for this route is around $525. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to San Diego?
The average bus travel time from Syracuse to San Diego is 3d 4h, covering a distance of 3737 km. The quickest bus can get you there in 2d 23h and is operated by Greyhound.
Which bus companies service the Syracuse to San Diego route?
What are the earliest and latest departure times for the bus from Syracuse to San Diego?
The earliest bus departs from Syracuse to San Diego at 1:15am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to San Diego?
A bus trip from Syracuse to San Diego generates an estimated 93 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to San Diego?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Syracuse to San Diego?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Syracuse to San Diego?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to San Diego?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to San Diego, CA, US was searched and found on Dec 25, 2025 with a price of $319To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to San Diego, CA, US, as early as possible.
You can expect to pay from $319 to $323 for a bus ticket from Syracuse, US to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $319 which is on 2025-12-25.
