Bus Tickets from Syracuse, NY to Winston-Salem, NC

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Compare 2 ways to go from Syracuse to Winston-Salem

Bus
Average PriceUS$161 - US$221Average Duration22h 40m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$252 - US$252Average Duration1d 5h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Syracuse to Winston-Salem

Among the sustainable travel choices, the bus stands out as a good way to reach Winston-Salem. The journey takes about 22 hours 40 minutes, and with fares starting at just US$161, it presents an excellent value for a comfortable ride.

4bus per day
22h 40mAverage Duration
US$161Cheapest ticket
21kgCO₂ emissions

Bus Syracuse to Winston-Salem: Trip Overview

Average Ticket PriceUS$197
Average Bus Trip Duration22h 40m
Number of daily buses4
Earliest bus departure12:00pm
Distance851 km
Latest bus departure9:00pm

Syracuse to Winston-Salem Bus

Busbud helps you find a bus from Syracuse to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Syracuse to Winston-Salem from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Syracuse to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Syracuse - Winston-Salem

  1. How long is the trip from Syracuse to Winston-Salem by bus?

    The typical travel time from Syracuse to Winston-Salem by bus is around 22h 40m. The fastest bus on this trip will get to Winston-Salem in 18h 35m

  2. What is the travel distance from Syracuse to Winston-Salem?

    The distance covered from Syracuse to Winston-Salem is 850 km (527 miles).

  3. What are the departure and arrival locations for buses traveling from Syracuse to Winston-Salem?

    Buses traveling this route start their trip at Syracuse Airport, in Syracuse, and end it at Winston Salem Greyhound Bus Station, in Winston-Salem.

  4. What is the cheapest way to go from Syracuse to Winston-Salem?

    Taking the bus is the cheapest option to travel from Syracuse to Winston-Salem. The ticket price for this bus starts at US$161, making this your best choice for this trip.

  5. How much does the bus ticket cost from Syracuse to Winston-Salem?

    The bus fare from Syracuse to Winston-Salem is approximately US$197.

  6. Is there an overnight bus from Syracuse to Winston-Salem?

    Yes! Catch buses leaving from Syracuse until 9:00pm and reaching Winston-Salem on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-11
US$153
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busbud logoThe cheapest trip from Syracuse to Winston-Salem was searched and found on May 11, 2025 with a price of US$153

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Winston-Salem, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Syracuse and Winston-Salem!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Syracuse to Winston-Salem, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Syracuse to Winston-Salem that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Syracuse to Winston-Salem.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Syracuse to Winston-Salem?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Syracuse by bus?

Bus from Syracuse to Winston-Salem

You can also go to Winston-Salem by train

Train from Syracuse to Winston-Salem

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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