Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | BILOXI | CheapestFastest | ||||
| Bus | Tupelo (Brothers Quick Stop) | BILOXI | No tags |
Last refresh of the prices: Last Friday at 11:14 AM CST.
Get from Tupelo to Biloxi
The journey takes about 15 hours 45 minutes, and with fares starting at just $179, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87442 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $179
Frequently asked questions about travelling from Tupelo to Biloxi by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Biloxi?
The cheapest bus tickets from Tupelo to Biloxi start from $179. The average price for this route is around $207. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Biloxi?
The average bus travel time from Tupelo to Biloxi is 15h 45m, covering a distance of 428 km. The quickest bus can get you there in 15h 45m and is operated by Greyhound.
Which bus companies service the Tupelo to Biloxi route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Tupelo to Biloxi?
The earliest bus departs from Tupelo to Biloxi at 10:55am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Tupelo to Biloxi?
A bus trip from Tupelo to Biloxi generates an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Biloxi was searched and found on Dec 23, 2025 with a price of $205To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Biloxi, as early as possible.
You can expect to pay from $205 to $348 for a bus ticket from Tupelo to Biloxi based on the last 2 days. You can expect to find the cheapest price for the trip at $205 which is on 2025-12-23.
