Bus Tickets from Tyler to Des Moines

Next departures

Next departures for Tyler to Des Moines on November 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
    		Tyler, TX
    		Des MoinesCheapestFastest

    Last refresh of the prices: Yesterday at 8:00 PM CDT.

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    Get from Tyler to Des Moines

    This route is served by bus only

    The journey takes about 1 day, 17 hours 25 minutes, and with fares starting at just US$232, it presents an excellent value for a comfortable ride.

    1bus per day
    1d 17hAverage Duration
    1039 kmDistance
    26kgCO₂ emissions

    Bus Tyler to Des Moines: Trip Overview

    Average Ticket PriceUS$232
    Average Bus Trip Duration1d 17h
    Number of daily buses1
    Earliest bus departure9:10pm
    Distance1039 km

    Tyler to Des Moines Bus

    Busbud helps you find a bus from Tyler to Des Moines. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

    We make sure you can find a bus service from Tyler to Des Moines from the most reliable bus companies operating this trip.

    From cheap bus tickets to more luxurious buses travelling from Tyler to Des Moines, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

    Frequently asked questions on the trip Tyler - Des Moines

    1. How far is Tyler from Des Moines?

      The distance between Tyler and Des Moines is around 1041 km (646 miles).

    2. What are the departure and arrival locations for buses traveling from Tyler to Des Moines?

      Buses traveling this route start their trip at Tyler Greyhound, in Tyler, and end it at Jefferson/Trailways Depot, in Des Moines.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    10-31
    No data
    11-01
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    Today
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    11-03
    US$224
    11-04
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    11-05
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    11-06
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    11-07
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    busbud logoThe cheapest trip from Tyler to Des Moines was searched and found on Nov 3, 2025 with a price of US$224

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tyler to Des Moines, as early as possible.

    You can expect to pay from US$224 to US$224 for a bus ticket from Tyler to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at US$224 which is on 2025-11-03.

    About Bus Travel

    Bus Travel Tips

    Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tyler and Des Moines!

    Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tyler to Des Moines, get comfy and count the stars.

    Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tyler to Des Moines that are otherwise impossible to come by with a plane.

    Tune out to the fine sounds of your best music playlist on your bus trip from Tyler to Des Moines while indulging in miles on end of beautiful scenic views.

    Did you know?

    Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

    It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

    Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

    Will you be returning to Tyler by bus?

    Bus from Des Moines to Tyler

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