Compare 2 ways to go from Greenville to Indianapolis
Busbud recommends taking the bus from Greenville to IndianapolisAmong the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 19 hours 10 minutes, and with fares starting at just US$78, it presents an excellent value for a comfortable ride.
Train Greenville, SC to Indianapolis: Trip Overview
Please note, this information is subject to change
Train companies
Based on 5418 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at US$139
Greenville to Indianapolis Train
Busbud helps you find a train from Greenville to Indianapolis. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
We make it our job to connect you with the most dependable companies that offer train service from Greenville to Indianapolis.
Discover how much the train trip from Greenville to Indianapolis will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.
Frequently asked questions on the trip Greenville, SC - Indianapolis
How much does a cheap train ticket from Greenville to Indianapolis cost?
The average train ticket price from Greenville to Indianapolis is US$196. The best way to find cheap train tickets from Greenville to Indianapolis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the trip from Greenville to Indianapolis?
A train trip between Greenville and Indianapolis is around 1d 2h, although the fastest train will take about 1d 2h. This is the time it takes to travel the 641 km that separates the two cities.
How many daily trains are there between Greenville and Indianapolis?
The number of trains from Greenville to Indianapolis can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Greenville to Indianapolis by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Greenville to Indianapolis?
When taking the train from Greenville to Indianapolis, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Indianapolis was searched and found on Aug 22, 2025 with a price of US$188To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Indianapolis, as early as possible.
You can expect to pay from US$188 to US$646 for a train ticket from Greenville, SC to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$195 which is on 2025-08-27.
About Train Travel
Train Travel Tips
There are many train stations in the world, check out the station pages on Busbud to get all information you need.
Whether you take a regional or high-speed train to Indianapolis, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
With up to 30x less CO2 emissions for your train journey between Greenville and Indianapolis, the train is an ecological alternative to flights or personal cars.
Create your real-life musical score by curating a personalized train travel playlist - the perfect accompaniment to your train ride from Greenville to Indianapolis.
Did you know?
The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date.
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
Japanese trains are always on time, it is extremely infrequent to see breakdowns during peak periods. In the event of a delay of more than 5 minutes, the crew will personally apologize to each passenger.
Top Travelled Train Routes
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