Cheap buses leaving today
One passenger / one way
- This trip is recommended because it is the: Cheapest + Fastest
- Departure time: May 29 atDeparture city: GreenvilleDeparture location: 1116 Woodruff RdArrival time: May 30 atDestination city: IndianapolisDestination location: Indianapolis Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration:
Last refresh of the prices: Yesterday at 1:32 PM EDT.
Prices and availability are subject to change.
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Compare 2 ways to go from Greenville to Indianapolis
Busbud recommends taking the bus from Greenville to IndianapolisAmong the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 16 hours 55 minutes, and with fares starting at just US$121, it presents an excellent value for a comfortable ride.
Bus Greenville to Indianapolis: Trip Overview
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Greenville to Indianapolis Bus
Busbud helps you find a bus from Greenville to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Greenville to Indianapolis.
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Where are the popular stops in Greenville and Indianapolis?
Frequently asked questions on the trip Greenville (SC) - Indianapolis
How long is the bus trip from Greenville to Indianapolis?
The bus ride from Greenville to Indianapolis takes 16h 55m, on average. For the shortest travel time, select the fastest bus available, which will take you to Indianapolis in about 15h 30m.
How far is Greenville from Indianapolis?
The distance covered from Greenville to Indianapolis is 641 km (398 miles).
What are the departure and arrival locations for buses traveling from Greenville to Indianapolis?
Buses traveling this route start their trip at Guadalajara Supermarket Bus Stop, in Greenville, and end it at Greyhound Amtrak Station, in Indianapolis.
What is the cheapest way to go from Greenville to Indianapolis?
Taking the bus is the most budget-friendly option to travel from Greenville to Indianapolis. The ticket price for this bus starts at US$121, making this your best choice for this trip.
How much does it cost to take the bus from Greenville to Indianapolis?
The bus fare from Greenville to Indianapolis is approximately US$132.
Can I take an overnight bus from Greenville to Indianapolis?
Yes! Catch buses leaving from Greenville until 10:00pm and reaching Indianapolis on the following day.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville to Indianapolis was searched and found on May 27, 2025 with a price of US$122To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Indianapolis, as early as possible.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Greenville and Indianapolis!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Greenville to Indianapolis.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Greenville to Indianapolis will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Indianapolis.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Greenville to Indianapolis?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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