Bus from Chicago to Syracuse, US: Tickets & Timetables

Next bus departures

Next departures from Chicago to Syracuse on 29 April
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)Cheapest
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)Fastest
Greyhound Lines, Inc.Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)No tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)No tags

Last refresh of the prices: Yesterday at 11:13 CDT.

Compare 2 ways to travel from Chicago to Syracuse

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 12 hours 58 minutes and with fares starting at just US$60, it presents an excellent value for a comfortable ride.

1train per day
12h 58mAverage duration
589 milesDistance
86kgCO₂ emissions
Bus
Average priceUS$70 - US$277Average duration23h 45m
24kg CO₂e
Train
Average priceUS$60 - US$217Average duration12h 58m
86kg CO₂e

Frequently asked questions about travelling by bus from Chicago to Syracuse, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Chicago to Syracuse?

    The cheapest coach tickets from Chicago to Syracuse start from US$70. The average price for this route is around US$101. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Chicago to Syracuse?

    The average bus journey time from Chicago to Syracuse is 23h 45m, covering a distance of 590 miles. The fastest bus can take you there in 16h 20m and is operated by Greyhound.

  3. Which bus companies service the Chicago to Syracuse route?

    Several major bus companies operate on this route with 7 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Chicago to Syracuse?

    The earliest bus departs from Chicago to Syracuse at 10:15. And the latest bus departs at 19:40.

  5. What are the CO₂ emissions for the bus trip from Chicago to Syracuse?

    A bus journey from Chicago to Syracuse produces an estimated 23.763274999999997 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Chicago to Syracuse?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87544 reviews.

  7. Which company has the best Wi-Fi from Chicago to Syracuse?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Chicago to Syracuse?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Chicago to Syracuse?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
26/04
US$153
27/04
US$137
Today
US$153
29/04
US$121
30/04
US$116
01/05
US$114
02/05
US$119
03/05
US$117
busbud logoThe cheapest trip from Chicago to Syracuse, US was searched and found on 1 May 2026 with a price of US$114

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Syracuse, US as early as possible.

You can expect to pay from US$114 to US$164 for a bus ticket from Chicago to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$114, which is on 2026-05-01.

What's the cheapest way to go from Chicago to Syracuse, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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