Bus from Chicago to Syracuse, US: Tickets & Timetables

Next bus departures

Next departures from Chicago to Syracuse on 28 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
537-517 W. Jackson Blvd
Syracuse (Regional Transportation Center)Cheapest
FlixBusBus
Chicago 95Th & Dan Ryan
Syracuse (Regional Transportation Center)Fastest
FlixBusBus
Downtown Greyhound Station
Syracuse (Regional Transportation Center)No tags

Last refresh of the prices: Today at 01:14 CST.

Compare 2 ways to travel from Chicago to Syracuse

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Syracuse. The journey takes about 12 hours 58 minutes and with fares starting at just £46, it presents an excellent value for a comfortable ride.

1train per day
12h 58mAverage duration
589 milesDistance
86kgCO₂ emissions
Bus
Average price£56 - £310Average duration1d
24kg CO₂e
Train
Average price£46 - £167Average duration12h 58m
86kg CO₂e

Frequently asked questions about travelling by bus from Chicago to Syracuse, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Chicago to Syracuse?

    The cheapest coach tickets from Chicago to Syracuse start from £56. The average price for this route is around £95. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Chicago to Syracuse?

    The average bus journey time from Chicago to Syracuse is 1d , covering a distance of 591 miles. The fastest bus can take you there in 23h 40m and is operated by FlixBus.

  3. Which bus companies service the Chicago to Syracuse route?

    Several major bus companies operate on this route with 4 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Chicago to Syracuse?

    The earliest bus departs from Chicago to Syracuse at 10:00. And the latest bus departs at 19:40.

  5. What are the CO₂ emissions for the bus trip from Chicago to Syracuse?

    A bus journey from Chicago to Syracuse produces an estimated 24 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Chicago to Syracuse?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which company has the best Wi-Fi from Chicago to Syracuse?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Chicago to Syracuse?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Chicago to Syracuse?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
25/11
£76
26/11
£80
Today
No data
28/11
£196
29/11
£104
30/11
No data
01/12
No data
02/12
£82
busbud logoThe cheapest trip from Chicago to Syracuse, US was searched and found on 25 Nov 2025 with a price of £76

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Syracuse, US as early as possible.

You can expect to pay from £76 to £201 for a bus ticket from Chicago to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at £82, which is on 2025-12-02.

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