Bus from Des Moines to Chicago: Tickets & Timetables

Next bus departures

Next departures from Des Moines to Chicago on 14 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Des Moines
Downtown Greyhound StationCheapest
Jefferson LinesBus
    Des Moines
    Chicago (Bus Station)Fastest
    Greyhound Lines, Inc.Bus
    Des Moines
    Downtown Greyhound StationNo tags
    Greyhound Lines, Inc. + FlixBus
    Bus
    Des Moines
    Chicago 95Th & Dan RyanNo tags
    Greyhound Lines, Inc.Bus
    Des Moines
    Downtown Greyhound StationNo tags

    Last refresh of the prices: Today at 21:45 CST.

    Get from Des Moines to Chicago

    This route is served by bus only

    The journey takes about 9 hours 5 minutes, and with fares starting at just £36, it presents an excellent value for a comfortable ride.

    7bus per day
    9h 5mAverage duration
    307 milesDistance
    12kgCO₂ emissions

    Frequently asked questions about travelling by bus from Des Moines to Chicago

    Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

    1. How much is the bus ticket from Des Moines to Chicago?

      The cheapest coach tickets from Des Moines to Chicago start from £36. The average price for this route is around £57. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

    2. How long is the bus journey from Des Moines to Chicago?

      The average bus journey time from Des Moines to Chicago is 9h 5m, covering a distance of 307 miles. The fastest bus can take you there in 6h and is operated by Jefferson Lines.

    3. Which bus companies service the Des Moines to Chicago route?

      Several major bus companies operate on this route with 7 buses available per day, including services from Greyhound, Jefferson Lines, Burlington Trailways.

    4. What is the earliest and latest departure time for the bus from Des Moines to Chicago?

      The earliest bus departs from Des Moines to Chicago at 00:01. And the latest bus departs at 23:45.

    5. What are the CO₂ emissions for the bus trip from Des Moines to Chicago?

      A bus journey from Des Moines to Chicago produces an estimated 12 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

    6. Which is the best bus company from Des Moines to Chicago?

      According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.

    7. Which company has the best Wi-Fi from Des Moines to Chicago?

      Based on Busbud reviews, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

    8. Which bus company offers the most punctual service from Des Moines to Chicago?

      According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.

    9. Which bus company has the cleanest buses from Des Moines to Chicago?

      According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    09/12
    £72
    10/12
    £77
    Today
    £57
    12/12
    £79
    13/12
    £52
    14/12
    £42
    15/12
    £41
    16/12
    £40
    busbud logoThe cheapest trip from Des Moines to Chicago was searched and found on 16 Dec 2025 with a price of £40

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Chicago as early as possible.

    You can expect to pay from £40 to £87 for a bus ticket from Des Moines to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £40, which is on 2025-12-16.

    Usually Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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