Find coaches from Detroit, MI to Winston-Salem

Next departures

Next departures from Detroit to Winston-Salem on 9 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Detroit Bus Station
Winston Salem Greyhound Bus StationCheapestFastest
Greyhound Lines, Inc.
Detroit Bus Station
Winston Salem Greyhound Bus StationNo tags

Last refresh of the prices: Today at 13:56 EDT.

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Bus Detroit, MI to Winston-Salem: Trip Overview

Average ticket priceUS$107
Average bus trip duration14h
Number of daily buses2
Earliest bus departure06:40
Distance456 miles
Latest bus departure20:15

Detroit to Winston-Salem Bus

Busbud helps you find a bus from Detroit to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Detroit to Winston-Salem from the most reliable bus companies operating this trip.

Discover how much the bus trip from Detroit to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Detroit, MI - Winston-Salem

  1. How far is Winston-Salem from Detroit by coach?

    The journey from Detroit to Winston-Salem by coach covers an approximate distance of 456 miles (735 km).

  2. Is there a way to reach Winston-Salem from Detroit without flying?

    To travel from Detroit to Winston-Salem without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/10
No data
07/10
US$90
Today
US$82
09/10
US$96
10/10
US$82
11/10
US$80
12/10
No data
13/10
No data
busbud logoThe cheapest trip from Detroit, MI to Winston-Salem was searched and found on 11 Oct 2025 with a price of US$80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Winston-Salem as early as possible.

You can expect to pay from US$80 to US$218 for a bus ticket from Detroit, MI to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$80, which is on 2025-10-11.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Detroit and Winston-Salem!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Winston-Salem, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Detroit to Winston-Salem will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Detroit, MI by bus?

Bus from Winston-Salem to Detroit, MI

Why choose Busbud?

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