Find coaches from Detroit (MI) to Winston-Salem

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Today3 Jun
from US$115
Tomorrow4 Jun
Thu5 Jun
Fri6 Jun
Sat7 Jun
Sun8 Jun
Mon9 Jun
Tue10 Jun

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: 3 June at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: 4 June at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Detroit to Winston-Salem: Trip Overview

Average ticket priceUS$145
Average bus trip duration13h 55m
Number of daily buses1
Earliest bus departure06:40
Distance456 miles
Latest bus departure20:15

Detroit to Winston-Salem Bus

Busbud helps you find a bus from Detroit to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Detroit to Winston-Salem from the most reliable bus companies operating this trip.

Discover how much the bus trip from Detroit to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Detroit (MI) - Winston-Salem

  1. What is the cheapest way to go from Detroit to Winston-Salem?

    For coach travel from Detroit to Winston-Salem, ticket prices typically start at US$85 and can reach a maximum of US$292. These prices can change depending on factors like the date, the class and the coach company you choose. Use Busbud to compare prices and amenities offered by different companies, ensuring you find the most favorable deals and promotions.

  2. How long does it take to travel from Detroit to Winston-Salem by bus?

    The coach journey between Detroit and Winston-Salem lasts about 13h 55m. The fastest coach journey typically takes 13h 55m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. When is the first coach from Detroit to Winston-Salem?

    The first coach from Detroit to Winston-Salem leaves at 06:40. Keep in mind that departure times might change on weekends and holidays.

  4. How far is Winston-Salem from Detroit by coach?

    The journey from Detroit to Winston-Salem by coach covers an approximate distance of 456 miles (735 km).

  5. Is there a way to reach Winston-Salem from Detroit without flying?

    To travel from Detroit to Winston-Salem without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

  6. Is there am overnight bus from Detroit to Winston-Salem?

    Yes, you can find coaches leaving until 20:15 and arriving the next day. Make sure to bring a snack and a blanket to keep yourself feeling comfortable during the night.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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Today
US$107
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busbud logoThe cheapest trip from Detroit to Winston-Salem was searched and found on 3 Jun 2025 with a price of US$107

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit to Winston-Salem as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Detroit and Winston-Salem!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Winston-Salem, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Detroit to Winston-Salem will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Detroit by bus?

Bus from Detroit to Winston-Salem

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