How much is the bus ticket from Indianapolis to St. Louis?

The cheapest coach tickets from Indianapolis to St. Louis start from £26. The average price for this route is around £38. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Indianapolis to St. Louis?

The average bus journey time from Indianapolis to St. Louis is 4h 20m, covering a distance of 230 miles. The fastest bus can take you there in 3h 55m and is operated by Greyhound .

Which bus companies service the Indianapolis to St. Louis route?

Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound , Amtrak , Burlington Trailways , FlixBus .

What is the earliest and latest departure time for the bus from Indianapolis to St. Louis?

The earliest bus departs from Indianapolis to St. Louis at 03:30. And the latest bus departs at 20:05.

What are the CO₂ emissions for the bus trip from Indianapolis to St. Louis?

A bus journey from Indianapolis to St. Louis produces an estimated 9 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from Indianapolis to St. Louis?

According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways , with an average rating of 4.2 out of 5 stars based on 20 reviews.

Which company has the best Wi-Fi from Indianapolis to St. Louis?

Based on Busbud reviews, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

Which bus company offers the most punctual service from Indianapolis to St. Louis?

According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways , with a punctuality rating of 5.0 out of 5 stars.

Which bus company has the cleanest buses from Indianapolis to St. Louis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways , with a cleanliness rating of 5.0 out of 5 stars.

Bus Indianapolis to St. Louis from £27 | Refundable Tickets

Next departures

Next departures from Indianapolis to St. Louis on 5 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 6 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 7 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	CheapestFastest
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	No tags
06:40	Greyhound Amtrak Station	6h 21m	12:01	Gateway Station	No tags
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Next departures from Indianapolis to St. Louis on 8 December
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
11:25	Indianapolis Bus Station	4h 55m	15:20	Gateway Station	Cheapest
03:30	Indianapolis Bus Station	3h 55m	06:25	Gateway Station	Fastest
20:05	Indianapolis Bus Station	4h 20m	23:25	Gateway Station	No tags

Last refresh of the prices: Today at 12:01 EST.

Compare 2 ways to travel from Indianapolis to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 4 hours 20 minutes and with fares starting at just £26, it presents an excellent value for a comfortable ride.

3bus per day

4h 20mAverage duration

230 milesDistance

9kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£26 - £67	Average duration4h 20m	CO₂ emissions 9kg CO₂e
Train	Average price£50 - £425	Average duration17h 23m	CO₂ emissions 34kg CO₂e

Where are the popular stops in Indianapolis and St. Louis?

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,414 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87414 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £26

Greyhound Indianapolis St. Louis recent customer reviews

The bus had some problems. Air conditioning was malfunctioning, and none of the outlets worked. There was also considerable damage to the seats that should have been repaired. The counter clerk was very friendly and helpful, but the bus driver seemed to be in a very bad mood and possibly ill, loudly coughing up phlegm the entire trip, and he gave us no indication of how late the bus was going to arrive. I will not ride Greyhound again if I can possibly avoid it.

Tremain X.

25 September 2019

The 3:15 bus never arrived so I was forced to wait 6 hours at the station for the next departure. This was very poorly communicated to passengers and no effort was made for any sort of reimbursement. I will absolutely never use Greyhound again.

Matthew N.

16 August 2018

Amtrak

4/55,624 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

WiFi3.6

Burlington Trailways

4/520 reviews

Staff5

Timeliness5

Cleanliness5

WiFi5

FlixBus

3.5/511,522 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

WiFi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from Indianapolis to St. Louis

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Indianapolis to St. Louis?
The cheapest coach tickets from Indianapolis to St. Louis start from £26. The average price for this route is around £38. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Indianapolis to St. Louis?
The average bus journey time from Indianapolis to St. Louis is 4h 20m, covering a distance of 230 miles. The fastest bus can take you there in 3h 55m and is operated by Greyhound.
Which bus companies service the Indianapolis to St. Louis route?
Several major bus companies operate on this route with 3 buses available per day, including services from Greyhound, Amtrak, Burlington Trailways, FlixBus.
What is the earliest and latest departure time for the bus from Indianapolis to St. Louis?
The earliest bus departs from Indianapolis to St. Louis at 03:30. And the latest bus departs at 20:05.
What are the CO₂ emissions for the bus trip from Indianapolis to St. Louis?
A bus journey from Indianapolis to St. Louis produces an estimated 9 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Indianapolis to St. Louis?
According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.
Which company has the best Wi-Fi from Indianapolis to St. Louis?
Based on Busbud reviews, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.
Which bus company offers the most punctual service from Indianapolis to St. Louis?
According to Busbud traveller reviews, the most punctual bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to St. Louis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

02/12

£34

03/12

£30

Today

£36

05/12

£31

06/12

£29

07/12

£28

08/12

£27

09/12

No data

The cheapest trip from Indianapolis to St. Louis was searched and found on 8 Dec 2025 with a price of £27

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to St. Louis as early as possible.

You can expect to pay from £27 to £133 for a bus ticket from Indianapolis to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at £27, which is on 2025-12-08.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.