Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Boston (South Station) | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Knoxville Bus Station | Brookline | Fastest | ||||
 | Bus | Knoxville Bus Station | Boston (South Station) | No tags |
Last refresh of the prices: Yesterday at 15:47 EST.
Get from Knoxville to Boston
The journey takes about 1 day, 6 hours 50 minutes, and with fares starting at just £78, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Boston?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Based on 87519 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at £77
Frequently asked questions about travelling by bus from Knoxville, TN to Boston, MA, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Knoxville to Boston?
The cheapest coach tickets from Knoxville to Boston start from £78. The average price for this route is around £188. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Knoxville to Boston?
The average bus journey time from Knoxville to Boston is 1d 6h, covering a distance of 812 miles. The fastest bus can take you there in 23h 55m and is operated by Greyhound.
Which bus companies service the Knoxville to Boston route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Knoxville to Boston?
The earliest bus departs from Knoxville to Boston at 22:00. And the latest bus departs at 22:50.
What are the CO₂ emissions for the bus trip from Knoxville to Boston?
A bus journey from Knoxville to Boston produces an estimated 33 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Boston, MA, US was searched and found on 2 Feb 2026 with a price of £155To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Boston, MA, US as early as possible.
