Find coaches from Knoxville, TN to Key West, FL

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Bus Knoxville to Key West: Trip Overview

Average ticket priceUS$160
Average bus trip duration1d 14h
Number of daily buses2
Earliest bus departure19:05
Distance800 miles

Knoxville to Key West Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Key West.

Bus service from Knoxville to Key West will be provided by the most trusted bus companies.

Discover how much the bus trip from Knoxville to Key West will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Knoxville - Key West

  1. How much does a bus ticket from Knoxville to Key West cost?

    The bus ticket price from Knoxville to Key West starts at US$160. The best way to find cheap bus tickets from Knoxville to Key West is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Knoxville to Key West?

    The average travel time between Knoxville and Key West is around 1d 14h, although the fastest bus will take about 1d 14h. This is the time it takes to travel the 798 miles that separates the two cities.

  3. How many daily bus connections are there between Knoxville and Key West?

    The number of buses from Knoxville to Key West can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Knoxville to Key West by comparing and selecting the bus that fits your travel style and budget on Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
18/05
No data
19/05
US$153
Today
No data
21/05
No data
22/05
US$153
23/05
No data
24/05
No data
25/05
US$153
busbud logoThe cheapest trip from Knoxville to Key West was searched and found on 19 May 2025 with a price of US$153

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Key West as early as possible.

You can expect to pay from US$153 to US$202 for a bus ticket from Knoxville to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at US$153, which is on 2025-05-22.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Key West but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Knoxville to Key West, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Knoxville to Key West will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Key West.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

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