Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Key West Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Knoxville Bus Station | Caroline St | No tags | ||||
Greyhound + FlixBus | Bus | Knoxville Bus Station | Caroline St | No tags | ||||
| Bus | Knoxville Bus Station | Key West Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Knoxville Bus Station | Caroline St | No tags |
Get from Knoxville to Key West
The journey takes about 1 day, 14 hours 5 minutes and with fares starting at just $176, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Key West?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Knoxville, TN to Key West by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Key West?
The cheapest bus tickets from Knoxville to Key West start from $176. The average price for this route is around $176. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Key West?
The average bus trip duration from Knoxville to Key West is 1d 14h, covering a distance of 800 miles (1289 km). The quickest bus can get you there in 1d 14h and is operated by Greyhound.
Which bus companies service the Knoxville to Key West route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Knoxville to Key West?
The earliest bus departs from Knoxville to Key West at 7:25pm. And the latest bus departs at 10:50pm.
What are the CO₂ emissions for the bus trip from Knoxville to Key West?
A bus trip from Knoxville to Key West generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
