Bus Tickets from Knoxville, TN to Key West, FL

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Bus Knoxville to Key West: Trip Overview

Average ticket price$160
Average bus trip duration1d 14h
Number of daily buses2
Earliest bus departure7:05pm
Distance800 miles (1289 km)

Knoxville to Key West Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Key West.

Bus service from Knoxville to Key West will be provided by the most trusted bus companies.

Discover how much the bus trip from Knoxville to Key West will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Knoxville - Key West

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/18
No data
05/19
$153
Today
No data
05/21
No data
05/22
$153
05/23
No data
05/24
No data
05/25
$153
busbud logoThe cheapest trip from Knoxville to Key West was searched and found on May 19, 2025 with a price of $153

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville to Key West, as early as possible.

You can expect to pay from $153 to $202 for a bus ticket from Knoxville to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $153 which is on 2025-05-22.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Key West but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Knoxville to Key West, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Knoxville to Key West will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Key West.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

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