Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Pittsburgh Intermodal Station | Cheapest | ||||
| Bus | Knoxville Bus Station | Pittsburgh Intermodal Station | Fastest |
Last refresh of the prices: Yesterday at 04:49 EST.
Get from Knoxville to Pittsburgh
The journey takes about 19 hours, and with fares starting at just £110, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Pittsburgh?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Pittsburgh
- A55 11th St, Pittsburgh, PA 15222, USA
- B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Compare bus companies
Based on 87500 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £110
Frequently asked questions about travelling by bus from Knoxville, TN to Pittsburgh
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Knoxville to Pittsburgh?
The cheapest coach tickets from Knoxville to Pittsburgh start from £110. The average price for this route is around £138. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Knoxville to Pittsburgh?
The average bus journey time from Knoxville to Pittsburgh is 19h, covering a distance of 372 miles. The fastest bus can take you there in 19h and is operated by Greyhound.
Which bus companies service the Knoxville to Pittsburgh route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Knoxville to Pittsburgh?
The earliest bus departs from Knoxville to Pittsburgh at 18:10. And the latest bus departs at 22:50.
What are the CO₂ emissions for the bus trip from Knoxville to Pittsburgh?
A bus journey from Knoxville to Pittsburgh produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Pittsburgh was searched and found on 14 Jan 2026 with a price of £111To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Pittsburgh as early as possible.
