Bus Tickets from Knoxville, TN to Pittsburgh

Next departures

Next departures for Knoxville to Pittsburgh on October 11
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Knoxville Bus Station
Pittsburgh Intermodal StationCheapest
Greyhound Lines, Inc.
Knoxville Bus Station
Pittsburgh Intermodal StationFastest

Last refresh of the prices: Yesterday at 10:51 AM EDT.

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Bus Knoxville, TN to Pittsburgh: Trip Overview

Average ticket price$113
Average bus trip duration23h 25m
Number of daily buses1
Earliest bus departure6:10pm
Distance372 miles (600 km)
Latest bus departure10:50pm

Knoxville to Pittsburgh Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Knoxville to Pittsburgh.

We make sure you can find a bus service from Knoxville to Pittsburgh from the most reliable bus companies operating this trip.

Discover how much the bus trip from Knoxville to Pittsburgh will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Knoxville, TN - Pittsburgh

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/09
No data
10/10
$104
Today
$203
10/12
No data
10/13
No data
10/14
No data
10/15
No data
10/16
No data
busbud logoThe cheapest trip from Knoxville, TN to Pittsburgh was searched and found on Oct 10, 2025 with a price of $104

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Pittsburgh, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Knoxville to Pittsburgh but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Knoxville to Pittsburgh, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Knoxville to Pittsburgh will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Knoxville to Pittsburgh.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Knoxville, TN by bus?

Bus from Pittsburgh to Knoxville, TN

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