Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | P+R Bouillon | Florenc | CheapestFastest |
Last refresh of the prices: Yesterday at 19:36 CET.
Get from Luxembourg to Prague
The journey takes about 15 hours 25 minutes, and with fares starting at just £33, it presents an excellent value for a comfortable ride.
Where are the popular stops in Luxembourg and Prague?
Stops in Luxembourg
- A
Luxembourg
3 Rue Genistre, 1623 Luxembourg, Luxembourg - B
Luxembourg Central Station
Place de la Gare 13, 1616 Luxembourg - C
Luxembourg Kirchberg
Rue Alphonse Weicker 4, 2721 Luxemburg, Luxemburg - D
Rue du Commerce
Rue du Commerce, 1351 Luxembourg, Luxembourg
Stops in Prague
- A
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - BAviatická, 161 08, Praha 6, Czechia
- CKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- DTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- F300/8 Wilsonova, 110 00 Praha, Czechia
Compare bus companies
Frequently asked questions about travelling by bus from Luxembourg to Prague
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Luxembourg to Prague?
The cheapest coach tickets from Luxembourg to Prague start from £33. The average price for this route is around £43. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Luxembourg to Prague?
The average bus journey time from Luxembourg to Prague is 15h 25m, covering a distance of 372 miles. The fastest bus can take you there in 8h 55m and is operated by RegioJet.
Which bus companies service the Luxembourg to Prague route?
Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Luxembourg to Prague?
The earliest bus departs from Luxembourg to Prague at 02:05. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Luxembourg to Prague?
A bus journey from Luxembourg to Prague produces an estimated 15 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Luxembourg to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.
Which company has the best Wi-Fi from Luxembourg to Prague?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Luxembourg to Prague?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Luxembourg to Prague?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Luxembourg to Prague was searched and found on 2 Dec 2025 with a price of £30To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Prague as early as possible.
You can expect to pay from £30 to £69 for a bus ticket from Luxembourg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at £36, which is on 2025-12-05.
