Bus from Luxembourg to Prague: Tickets & Schedules

Next bus departures

Next departures for Luxembourg to Prague on December 4
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixbusBus
Luxembourg
Prague (Main Railway Station)Cheapest
RegioJetBus
P+R Bouillon
FlorencFastest
FlixbusBus
Luxembourg
Prague (Central Bus Station Florenc)No tags
FlixbusBus
Luxembourg
Prague (Central Bus Station Florenc)No tags
FlixbusBus
Luxembourg
Prague (Central Bus Station Florenc)No tags

Last refresh of the prices: Last Thursday at 9:04 AM CET.

Get from Luxembourg to Prague

This route is served by bus only

The journey takes about 15 hours 25 minutes and with fares starting at just $43, it presents an excellent value for a comfortable ride.

6bus per day
15h 25mAverage Duration
372 milesDistance
15kgCO₂ emissions

Frequently asked questions about traveling from Luxembourg to Prague by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Luxembourg to Prague?

    The cheapest bus tickets from Luxembourg to Prague start from $43. The average price for this route is around $56. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Luxembourg to Prague?

    The average bus trip duration from Luxembourg to Prague is 15h 25m, covering a distance of 372 miles (600 km). The quickest bus can get you there in 8h 55m and is operated by RegioJet.

  3. Which bus companies service the Luxembourg to Prague route?

    Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.

  4. What is the earliest and latest departure time for the bus from Luxembourg to Prague?

    The earliest bus departs from Luxembourg to Prague at 2:05am. And the latest bus departs at 11:25pm.

  5. What are the CO₂ emissions for the bus trip from Luxembourg to Prague?

    A bus trip from Luxembourg to Prague generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Luxembourg to Prague?

    According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.

  7. Which bus company has the best Wi-Fi from Luxembourg to Prague?

    Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

  8. Which bus company has the most timely service from Luxembourg to Prague?

    According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Luxembourg to Prague?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/30
$48
12/01
No data
Today
$39
12/03
No data
12/04
$46
12/05
$47
12/06
No data
12/07
$60
busbud logoThe cheapest trip from Luxembourg to Prague was searched and found on Dec 2, 2025 with a price of $39

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Luxembourg to Prague, as early as possible.

You can expect to pay from $39 to $90 for a bus ticket from Luxembourg to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2025-12-04.

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