Find coaches from Lyon to Siena

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Tomorrow6 Jul
Mon7 Jul
from US$76
Tue8 Jul
Wed9 Jul
Thu10 Jul
Fri11 Jul
Sat12 Jul
Sun13 Jul

Cheap buses leaving Monday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 7 July at
    Departure city: Lyon
    Departure location: Lyon Lyon Perrache Bus Station
    Arrival time: 8 July at
    Destination city: Siena
    Destination location: Siena Train Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 7 July at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: 7 July at
    Destination city: Siena
    Destination location: Siena Train Station
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: 7 July at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: 8 July at
    Destination city: Siena
    Destination location: Siena Train Station
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: 7 July at
    Departure city: Lyon
    Departure location: Lyon Lyon Perrache Bus Station
    Arrival time: 8 July at
    Destination city: Siena
    Destination location: Siena Train Station
    Operated by: ItabusItabus
    Vehicle: BusDuration:
  • Departure time: 7 July at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: 8 July at
    Destination city: Siena
    Destination location: Siena Train Station
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

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Bus Lyon to Siena: Trip Overview

Average ticket priceUS$106
Average bus trip duration15h 25m
Number of daily buses10
Earliest bus departure01:15
Distance363 miles
Latest bus departure23:30

Lyon to Siena Bus

Busbud helps you find a bus from Lyon to Siena. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Lyon to Siena will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Siena from Lyon, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Lyon - Siena

  1. What's the distance between Lyon and Siena by coach?

    The journey from Lyon to Siena by coach covers an approximate distance of 361 miles (581 km).

  2. How can I travel from Lyon to Siena avoiding air travel?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
03/07
No data
04/07
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Today
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06/07
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07/07
US$69
08/07
No data
09/07
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10/07
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busbud logoThe cheapest trip from Lyon to Siena was searched and found on 7 Jul 2025 with a price of US$69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Siena as early as possible.

You can expect to pay from US$69 to US$122 for a bus ticket from Lyon to Siena based on the last 2 days. You can expect to find the cheapest price for the trip at US$69, which is on 2025-07-07.

Usually Flixbus (FR) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Lyon and Siena!

Much more than a mere vehicle taking you from Lyon to Siena, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Lyon to Siena.

Tune out to the fine sounds of your best music playlist on your bus trip from Lyon to Siena while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Lyon by bus?

Bus from Lyon to Siena

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