Find coaches from Milano to Palermo

Next departures

Next departures from Milano to Palermo on 11 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Aeroporto Linate Airport (LIN)
Terminal Bus PalermoCheapest
Flixbus
Lampugnano bus station
Terminal Bus PalermoFastest
Flixbus
Lampugnano bus station
Terminal Bus PalermoNo tags
Flixbus
Milan (San Donato M3)
Terminal Bus PalermoNo tags
Flixbus
Milan (San Donato M3)
Terminal Bus PalermoNo tags

Last refresh of the prices: Last Tuesday at 02:54 CEST.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Milano to Palermo

Bus
Average priceUS$40 - US$255Average duration1d 2h
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$79 - US$141Average duration16h 40m
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milano to Palermo

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 40 minutes and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

1carpool per day
16h 40mAverage duration
US$79Cheapest ticket
37kgCO₂ emissions

Bus Milano to Palermo: Trip Overview

Average ticket priceUS$102
Average bus trip duration1d 2h
Number of daily buses13
Earliest bus departure03:05
Distance547 miles
Latest bus departure23:50

Milano to Palermo Bus

Busbud helps you find a bus from Milano to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milano to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milano to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milano - Palermo

  1. How far is Palermo from Milano by coach?

    The distance between Milano and Palermo by coach is approximately 551 miles (888 km).

  2. Is there a way to reach Palermo from Milano without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/10
US$237
09/10
US$126
Today
US$73
11/10
US$81
12/10
US$62
13/10
US$66
14/10
US$62
15/10
US$64
busbud logoThe cheapest trip from Milano to Palermo was searched and found on 14 Oct 2025 with a price of US$62

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo as early as possible.

You can expect to pay from US$62 to US$237 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$62, which is on 2025-10-14.

Usually Autoservizi Salemi will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milano to Palermo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Milano to Palermo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milano to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Milano to Palermo?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milano by bus?

Bus from Palermo to Milano

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Milano

Buses Leaving from Milano

Buses Going to Milano

Popular Buses Connecting Palermo

Buses Leaving from Palermo

Buses Going to Palermo