Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lampugnano bus station | Terminal Bus Palermo | CheapestFastest | ||||
| Bus | Lampugnano bus station | Terminal Bus Palermo | No tags | ||||
| Bus | Milan (San Donato M3) | Terminal Bus Palermo | No tags | ||||
| Bus | Milan (San Donato M3) | Terminal Bus Palermo | No tags | ||||
| Bus | Piazza I Maggio, 1 | Terminal Bus Palermo | No tags |
Last refresh of the prices: Today at 15:58 CET.
Compare 2 ways to travel from Milano to Palermo
Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 40 minutes and with fares starting at just £61, it presents an excellent value for a comfortable ride.
| Average price | Average duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average price£28 - £239 | Average duration1d 2h | 22kg CO₂e | ||
Carpool | Average price£61 - £110 | Average duration16h 40m | 37kg CO₂e |
Where are the popular stops in Milano and Palermo?
Stops in Milano
- AVia Giulio Natta, 228, 20151 Milano, Italy
- BPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- CVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Palermo
- AVia Tommaso Fazello, 16, 90123 Palermo PA, Italy
- BPunta Raisi, 90145, Palermo
- CPiazza Cairoli, 8-14, 90123 Palermo, Italy
- D90143 Palermo PA, Italy
- EVia Paolo Balsamo, 21, 90123 Palermo, Italy
- F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy
Compare bus companies
Frequently asked questions about travelling by bus from Milano to Palermo
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Milano to Palermo?
The cheapest coach tickets from Milano to Palermo start from £28. The average price for this route is around £85. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Milano to Palermo?
The average bus journey time from Milano to Palermo is 1d 2h, covering a distance of 547 miles. The fastest bus can take you there in 21h and is operated by Autoservizi Salemi.
Which bus companies service the Milano to Palermo route?
Several major bus companies operate on this route with 11 buses available per day, including services from FlixBus, Autoservizi Salemi, Itabus.
What is the earliest and latest departure time for the bus from Milano to Palermo?
The earliest bus departs from Milano to Palermo at 00:00. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Milano to Palermo?
A bus journey from Milano to Palermo produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Milano to Palermo?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 450 reviews.
Which company has the best Wi-Fi from Milano to Palermo?
Based on Busbud reviews, the bus company Autoservizi Salemi has the best Wi-Fi rating with a score of 3.9.
Which bus company offers the most punctual service from Milano to Palermo?
According to Busbud traveller reviews, the most punctual bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Milano to Palermo?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Palermo was searched and found on 3 Dec 2025 with a price of £56To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo as early as possible.
You can expect to pay from £56 to £151 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at £56, which is on 2025-12-03.
Usually Autoservizi Salemi will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
