What is the travel distance from Milano to Palermo?

The distance separating Milano and Palermo is 551 miles (888 km).

What are the departure and arrival stations when taking the bus from Milano to Palermo?

The majority of buses traveling from Milano to Palermo start their journey at Lampugnano and wind up at Terminal Bus Palermo. These are the most popular pick-up and drop-off locations on this route, but you could find others that could be a better fit for your travel plans.

What are the best sights and things to do in Palermo?

Once in Palermo, you can start exploring the city and discover its surroundings. The top sights and things to do are Galleria Regionale della Sicilia, Cattedrale di Palermo, Quattro Canti, Ballarò Market and Cappella Palatina.

Bus Milano to Palermo from $63 | Refundable Tickets

Next bus departures

Next departures for Milano to Palermo on November 25
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	CheapestFastest

Next departures for Milano to Palermo on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Cheapest
Bus	10:45am	Milan San Donato Bus Station	21h	7:45am	Terminal Bus Palermo	Fastest
Bus	10:00am	Lampugnano	21h 45m	7:45am	Terminal Bus Palermo	No tags
Bus	8:50am	Milan (San Donato M3)	1d 2h	11:00am	Terminal Bus Palermo	No tags
Bus	9:05am	Milan (Assago M2)	1d 1h	11:00am	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	CheapestFastest
Bus	9:40am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	7:05am	Piazza I Maggio, 1	1d 3h	11:00am	Terminal Bus Palermo	No tags
Bus	9:05am	Milan (Assago M2)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	5:25am	Milan (Malpensa Aeroporto Terminal 1)	1d 5h	11:00am	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 28
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:10am	Aeroporto Linate Airport (LIN)	1d 4h	2:25pm	Terminal Bus Palermo	Cheapest
Bus	10:45am	Milan San Donato Bus Station	21h	7:45am	Terminal Bus Palermo	Fastest
Bus	10:00am	Lampugnano	21h 45m	7:45am	Terminal Bus Palermo	No tags
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	No tags
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 29
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:10am	Aeroporto Linate Airport (LIN)	1d 4h	2:25pm	Terminal Bus Palermo	Cheapest
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Fastest
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	9:40am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	2:45pm	Milan (San Donato M3)	23h 40m	2:25pm	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 30
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:10am	Aeroporto Linate Airport (LIN)	1d 4h	2:25pm	Terminal Bus Palermo	Cheapest
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Fastest
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	10:00am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	2:45pm	Milan (San Donato M3)	23h 40m	2:25pm	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on December 1
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:05am	Piazza I Maggio, 1	1d 3h	11:00am	Terminal Bus Palermo	Cheapest
Bus	10:45am	Milan San Donato Bus Station	21h	7:45am	Terminal Bus Palermo	Fastest
Bus	10:00am	Lampugnano	21h 45m	7:45am	Terminal Bus Palermo	No tags
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	No tags
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on December 2
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	CheapestFastest
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	8:50am	Milan (San Donato M3)	1d 2h	11:00am	Terminal Bus Palermo	No tags
Bus	11:45am	Piazza I Maggio, 1	1d 2h	2:25pm	Terminal Bus Palermo	No tags
Bus	9:05am	Milan (Assago M2)	1d 1h	11:00am	Terminal Bus Palermo	No tags

Last refresh of the prices: Today at 7:15 AM CET.

Compare 2 ways to go from Milano to Palermo

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as the good way to reach Palermo. The journey takes about 16 hours 40 minutes and with fares starting at just $79, it presents an excellent value for a comfortable ride.

1carpool per day

16h 40mAverage Duration

550 milesDistance

37kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$36 - $308	Average Duration1d 2h	CO₂ emissions 22kg CO₂e
Carpool	Average Price$79 - $141	Average Duration16h 40m	CO₂ emissions 37kg CO₂e

Where are the popular stops in Milano and Palermo?

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page
B
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
C
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
D
Linate Airport
Visit page
E
Malpensa Airport
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Stops in Palermo

A
Terminal Bus Palermo
Via Tommaso Fazello, 16, 90123 Palermo PA, Italy
Visit page
B
Palermo Airport
Punta Raisi, 90145, Palermo
Visit page
C
Piazza Cairoli
Piazza Cairoli, 8-14, 90123 Palermo, Italy
Visit page
D
Fiera
90143 Palermo PA, Italy
Visit page
E
Via Paolo Balsamo, 21
Via Paolo Balsamo, 21, 90123 Palermo, Italy
Visit page
F
Via Paolo Balsamo, 31
Via Paolo Balsamo, 23-31, 90123 Palermo, Italy

Compare bus companies

FlixBus

3.5/511,440 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Autoservizi Salemi

4.5/5451 reviews

Staff4.9

Timeliness4.3

Cleanliness4.7

Wifi3.9

Itabus

4/5946 reviews

Staff4.3

Timeliness3

Cleanliness4.3

Wifi3.1

IT bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about traveling from Milano to Palermo by bus

What is the travel distance from Milano to Palermo?
What are the departure and arrival stations when taking the bus from Milano to Palermo?
What are the best sights and things to do in Palermo?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/23

$186

11/24

$168

Today

$109

11/26

$78

11/27

$78

11/28

$72

11/29

$64

11/30

$73

The cheapest trip from Milano to Palermo was searched and found on Nov 29, 2025 with a price of $64

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.

You can expect to pay from $64 to $186 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $64 which is on 2025-11-29.