Find coaches from Milano to Prague

Next departures

Next departures from Milano to Prague on 12 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Lampugnano bus station
Prague (Central Bus Station Florenc)Cheapest
Flixbus
Lampugnano bus station
Prague (Main Railway Station)Fastest
RegioJet
Lampugnano
FlorencNo tags
Flixbus
Aeroporto Linate Airport (LIN)
Prague (Central Bus Station Florenc)No tags
BlaBlaCar Bus
Milan Bergamo - Airport
FlorencNo tags

Last refresh of the prices: Today at 09:30 CEST.

Accepted payments

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Compare 2 ways to travel from Milano to Prague

Bus
Average priceUS$48 - US$298Average duration18h 10m
16kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$49 - US$49Average duration9h 30m
27kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milano to Prague

Among the sustainable travel choices, the carpool stands out as a good way to reach Prague. The journey takes about 9 hours 30 minutes and with fares starting at just US$49, it presents an excellent value for a comfortable ride.

1carpool per day
9h 30mAverage duration
US$49Cheapest ticket
27kgCO₂ emissions

Bus Milano to Prague: Trip Overview

Average ticket priceUS$85
Average bus trip duration18h 10m
Number of daily buses55
Earliest bus departure01:00
Distance398 miles
Latest bus departure23:45

Milano to Prague Bus

Busbud helps you find a bus from Milano to Prague. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from Milano to Prague will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Prague from Milano, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Milano - Prague

  1. What's the distance between Milano and Prague by coach?

    The distance between Milano and Prague by coach is approximately 401 miles (647 km).

  2. How can I travel from Milano to Prague avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/10
US$97
10/10
US$76
Today
US$72
12/10
US$78
13/10
US$61
14/10
US$56
15/10
US$65
16/10
US$52
busbud logoThe cheapest trip from Milano to Prague was searched and found on 16 Oct 2025 with a price of US$52

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Prague as early as possible.

You can expect to pay from US$52 to US$183 for a bus ticket from Milano to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at US$52, which is on 2025-10-16.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Prague!

Much more than a mere vehicle taking you from Milano to Prague, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Milano to Prague.

Tune out to the fine sounds of your best music playlist on your bus trip from Milano to Prague while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Milano by bus?

Bus from Prague to Milano

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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