Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Lampugnano bus station | Prague (Main Railway Station) | Cheapest | ||||
| Bus | Lampugnano bus station | Prague (Main Railway Station) | Fastest | ||||
| Bus | Aeroporto Linate Airport (LIN) | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Aeroporto Linate Airport (LIN) | Prague (Central Bus Station Florenc) | No tags | ||||
| Bus | Aeroporto Linate Airport (LIN) | Prague (Main Railway Station) | No tags |
Last refresh of the prices: Today at 7:21 PM CEST.
Get from Milano to Prague
The journey takes about 18 hours 25 minutes and with fares starting at just COP 185,035, it presents an excellent value for a comfortable ride.
Where are the popular stops in Milano and Prague?
Stops in Milano
- BPiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- CVia Giulio Natta, 228, 20151 Milano, Italy
- EVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CAviatická, 161 08, Praha 6, Czechia
- D
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
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Frequently asked questions about traveling from Milano to Prague by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milano to Prague?
The cheapest bus tickets from Milano to Prague start from COP 185,035. The average price for this route is around COP 317,889. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Prague?
The average bus trip duration from Milano to Prague is 18h 25m, covering a distance of 402 miles (647 km). The quickest bus can get you there in 12h 30m and is operated by FlixBus.
Which bus companies service the Milano to Prague route?
Several major bus companies operate on this route with 78 buses available per day, including services from FlixBus, RegioJet, BlaBlaCar Bus.
What is the earliest and latest departure time for the bus from Milano to Prague?
The earliest bus departs from Milano to Prague at 1:00am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Milano to Prague?
A bus trip from Milano to Prague generates an estimated 16.172325 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Milano to Prague?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1076 reviews.
Which bus company has the best Wi-Fi from Milano to Prague?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Milano to Prague?
According to Busbud traveler reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Milano to Prague?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Prague was searched and found on Jun 8, 2026 with a price of COP 205,607To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Prague, as early as possible.
You can expect to pay from COP 205,607 to COP 771,932 for a bus ticket from Milano to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at COP 205,607 which is on 2026-06-08.
