Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | Opelika (4th Street Station) | San Antonio Bus Station | CheapestFastest |
Last refresh of the prices: Yesterday at 17:43 CST.
Get from Opelika to San Antonio
The journey takes about 17 hours 40 minutes, and with fares starting at just £146, it presents an excellent value for a comfortable ride.
Where are the popular stops in Opelika and San Antonio?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Compare bus companies
Based on 87427 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £146
Frequently asked questions about travelling by bus from Opelika to San Antonio, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Opelika to San Antonio?
The cheapest coach tickets from Opelika to San Antonio start from £146. The average price for this route is around £146. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Opelika to San Antonio?
The average bus journey time from Opelika to San Antonio is 17h 40m, covering a distance of 806 miles. The fastest bus can take you there in 20h 25m and is operated by Greyhound.
Which bus companies service the Opelika to San Antonio route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Opelika to San Antonio?
The earliest bus departs from Opelika to San Antonio at 09:00. And the latest bus departs at 21:40.
What are the CO₂ emissions for the bus trip from Opelika to San Antonio?
A bus journey from Opelika to San Antonio produces an estimated 32 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Opelika to San Antonio, US was searched and found on 11 Dec 2025 with a price of £165To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Opelika to San Antonio, US as early as possible.
