Find coaches from Philadelphia (PA) to Knoxville (TN)

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Today2 Jun
Tomorrow3 Jun
from US$103
Wed4 Jun
Thu5 Jun
Fri6 Jun
Sat7 Jun
Sun8 Jun
Mon9 Jun

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 3 June at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 4 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 3 June at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 3 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 June at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 4 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 June at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 3 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 3 June at
    Departure city: Philadelphia
    Departure location: Schuylkill & Walnut
    Arrival time: 4 June at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Philadelphia to Knoxville: Trip Overview

Average ticket priceUS$95
Average bus trip duration22h 5m
Number of daily buses6
Earliest bus departure01:45
Distance548 miles
Latest bus departure20:45

Philadelphia to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Philadelphia to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Knoxville.

From cheap bus tickets to more luxurious buses travelling from Philadelphia to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Philadelphia (PA) - Knoxville (TN)

  1. What is the affordable way to go from Philadelphia to Knoxville?

    For coach travel from Philadelphia to Knoxville, ticket prices typically start at US$67 and can reach a maximum of US$172. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long does it take to travel from Philadelphia to Knoxville by bus?

    The average duration for a trip from Philadelphia to Knoxville by coach is around 22h 5m. The quickest coach journey typically takes 16h 10m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. When is the first coach from Philadelphia to Knoxville?

    The first coach to Knoxville from Philadelphia departs at 01:45. Keep in mind that departure times might change on weekends and holidays.

  4. How far is Knoxville from Philadelphia by coach?

    The distance between Philadelphia and Knoxville by coach is approximately 551 miles (888 km).

  5. Is there a way to reach Knoxville from Philadelphia without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

  6. Is there am overnight coach from Philadelphia to Knoxville?

    Yes, you can find buses leaving until 20:45 and arriving the next day. Make sure to bring a snack and a blanket to keep yourself feeling comfortable during the night.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
31/05
US$85
01/06
No data
Today
No data
03/06
US$97
04/06
No data
05/06
No data
06/06
US$104
07/06
No data
busbud logoThe cheapest trip from Philadelphia to Knoxville was searched and found on 31 May 2025 with a price of US$85

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to Knoxville as early as possible.

You can expect to pay from US$85 to US$127 for a bus ticket from Philadelphia to Knoxville based on the last 2 days. You can expect to find the cheapest price for the trip at US$97, which is on 2025-06-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Philadelphia to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Philadelphia to Knoxville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Philadelphia to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to Knoxville

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