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One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: 27 July atDeparture city: PhiladelphiaDeparture location: Schuylkill & WalnutArrival time: 28 July atDestination city: KnoxvilleDestination location: Knoxville Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - This trip is recommended because it is the: Fastest
- Departure time: 27 July atDeparture city: PhiladelphiaDeparture location: 199 Spring Garden St.Arrival time: 28 July atDestination city: KnoxvilleDestination location: Knoxville Bus StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: 27 July atDeparture city: PhiladelphiaDeparture location: Camden (Walter Rand Transportation Center)Arrival time: 28 July atDestination city: KnoxvilleDestination location: Knoxville Bus StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Bus Philadelphia, PA to Knoxville, TN: Trip Overview
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Philadelphia to Knoxville Bus
With Busbud, comparing and booking tickets for a bus from Philadelphia to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Knoxville.
From cheap bus tickets to more luxurious buses travelling from Philadelphia to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Philadelphia and Knoxville?
Frequently asked questions on the trip Philadelphia, PA - Knoxville, TN
How far is Knoxville from Philadelphia by coach?
The distance between Philadelphia and Knoxville by coach is approximately 551 miles (888 km).
Is there a way to reach Knoxville from Philadelphia without flying?
You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to Knoxville, TN was searched and found on 31 Jul 2025 with a price of US$76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Knoxville, TN as early as possible.
You can expect to pay from US$76 to US$132 for a bus ticket from Philadelphia, PA to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$76, which is on 2025-07-31.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Philadelphia to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Knoxville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Philadelphia to Knoxville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Philadelphia to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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