Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Philadelphia, 199 Spring Garden St | Knoxville Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Cherry Hill Mall | Knoxville Bus Station | No tags | ||||
FlixBus + Greyhound | Bus | Philadelphia (Logan Square) | Knoxville Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Philadelphia (Logan Square) | Knoxville Bus Station | No tags | ||||
 | Bus | 199 Spring Garden St. | Knoxville Bus Station | No tags |
Get from Philadelphia to Knoxville
The journey takes about 22 hours, and with fares starting at just £60, it presents an excellent value for a comfortable ride.
Where are the popular stops in Philadelphia and Knoxville?
Stops in Philadelphia
- BOff of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
- C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA - D
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA - E
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA - F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Frequently asked questions about travelling by bus from Philadelphia, PA to Knoxville, TN
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Philadelphia to Knoxville?
The cheapest coach tickets from Philadelphia to Knoxville start from £60. The average price for this route is around £97. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Philadelphia to Knoxville?
The average bus journey time from Philadelphia to Knoxville is 22h, covering a distance of 546 miles. The fastest bus can take you there in 16h and is operated by Greyhound.
Which bus companies service the Philadelphia to Knoxville route?
What is the earliest and latest departure time for the bus from Philadelphia to Knoxville?
The earliest bus departs from Philadelphia to Knoxville at 01:50. And the latest bus departs at 23:15.
What are the CO₂ emissions for the bus trip from Philadelphia to Knoxville?
A bus journey from Philadelphia to Knoxville produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Philadelphia to Knoxville?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87387 reviews.
Which company has the best Wi-Fi from Philadelphia to Knoxville?
Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Philadelphia to Knoxville?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Knoxville?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Philadelphia, PA to Knoxville, TN was searched and found on 2 Dec 2025 with a price of £74To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Knoxville, TN as early as possible.
You can expect to pay from £74 to £210 for a bus ticket from Philadelphia, PA to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at £74, which is on 2025-12-02.
