How much is the bus ticket from Pittsburgh to San Diego?

The cheapest coach tickets from Pittsburgh to San Diego start from £201. The average price for this route is around £276. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Pittsburgh to San Diego?

The average bus journey time from Pittsburgh to San Diego is 2d 15h, covering a distance of 2110 miles. The fastest bus can take you there in 2d 9h and is operated by Greyhound .

Which bus companies service the Pittsburgh to San Diego route?

Several major bus companies operate on this route with 10 buses available per day.

What is the earliest and latest departure time for the bus from Pittsburgh to San Diego?

The earliest bus departs from Pittsburgh to San Diego at 01:35. And the latest bus departs at 20:00.

What are the CO₂ emissions for the bus trip from Pittsburgh to San Diego?

A bus journey from Pittsburgh to San Diego produces an estimated 85 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Bus Pittsburgh to San Diego from £252 | Refundable Tickets

Next bus departures

Next departures from Pittsburgh to San Diego on 13 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	20:00	Pittsburgh Intermodal Station	3d 5h	22:15	Downtown SD (Seaport)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:35	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 10h	18:10	San Diego (Old Town-FlixBus)	No tags
	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:45	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 14h	22:15	Downtown SD (Seaport)	No tags

Next departures from Pittsburgh to San Diego on 14 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	20:00	Pittsburgh Intermodal Station	3d 5h	22:15	Downtown SD (Seaport)	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:35	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 10h	18:10	San Diego (Old Town-FlixBus)	No tags
	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:45	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 14h	22:15	Downtown SD (Seaport)	No tags

Next departures from Pittsburgh to San Diego on 15 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	20:00	Pittsburgh Intermodal Station	2d 20h	13:40	UCSD Health La Jolla Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:35	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 10h	18:10	San Diego (Old Town-FlixBus)	No tags
	Bus	10:50	Pittsburgh Intermodal Station	2d 16h	23:50	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	20:00	Pittsburgh Intermodal Station	2d 21h	14:10	San Diego (Old Town-FlixBus)	No tags

Next departures from Pittsburgh to San Diego on 16 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	01:35	Pittsburgh Intermodal Station	2d 15h	13:40	UCSD Health La Jolla Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:35	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:35	Pittsburgh Intermodal Station	2d 15h	14:10	San Diego (Old Town-FlixBus)	No tags
	Bus	10:50	Pittsburgh Intermodal Station	2d 16h	23:50	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 10h	18:10	San Diego (Old Town-FlixBus)	No tags

Next departures from Pittsburgh to San Diego on 17 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	20:00	Pittsburgh Intermodal Station	2d 20h	13:40	UCSD Health La Jolla Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:35	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:35	Pittsburgh Intermodal Station	2d 15h	14:10	San Diego (Old Town-FlixBus)	No tags
	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:45	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 10h	18:10	San Diego (Old Town-FlixBus)	No tags

Next departures from Pittsburgh to San Diego on 18 December
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	01:35	Pittsburgh Intermodal Station	2d 15h	13:40	UCSD Health La Jolla Station	Cheapest
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:35	UCSD Health La Jolla Station	Fastest
Greyhound Lines, Inc. + FlixBus	Bus	01:35	Pittsburgh Intermodal Station	2d 15h	14:10	San Diego (Old Town-FlixBus)	No tags
	Bus	10:50	Pittsburgh Intermodal Station	2d 9h	17:45	Greyhound Bus Stop	No tags
Greyhound Lines, Inc. + FlixBus	Bus	10:50	Pittsburgh Intermodal Station	2d 10h	18:10	San Diego (Old Town-FlixBus)	No tags

Last refresh of the prices: Last Sunday at 04:14 EST.

Get from Pittsburgh to San Diego

This route is served by bus only

The journey takes about 2 days, 15 hours 5 minutes, and with fares starting at just £201, it presents an excellent value for a comfortable ride.

10bus per day

2d 15hAverage duration

2110 milesDistance

85kgCO₂ emissions

Where are the popular stops in Pittsburgh and San Diego?

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA

Stops in San Diego

A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA
B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA
C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA
D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA
E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA
F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA

Compare bus companies

Greyhound

3.5/587,430 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

WiFi2.4

Based on 87430 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £229

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from Pittsburgh to San Diego, CA, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Pittsburgh to San Diego?
The cheapest coach tickets from Pittsburgh to San Diego start from £201. The average price for this route is around £276. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Pittsburgh to San Diego?
The average bus journey time from Pittsburgh to San Diego is 2d 15h, covering a distance of 2110 miles. The fastest bus can take you there in 2d 9h and is operated by Greyhound.
Which bus companies service the Pittsburgh to San Diego route?
Several major bus companies operate on this route with 10 buses available per day.
What is the earliest and latest departure time for the bus from Pittsburgh to San Diego?
The earliest bus departs from Pittsburgh to San Diego at 01:35. And the latest bus departs at 20:00.
What are the CO₂ emissions for the bus trip from Pittsburgh to San Diego?
A bus journey from Pittsburgh to San Diego produces an estimated 85 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/12

£410

12/12

£310

Today

£374

14/12

£252

15/12

£353

16/12

£300

17/12

£299

18/12

£371

The cheapest trip from Pittsburgh to San Diego, CA, US was searched and found on 14 Dec 2025 with a price of £252

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to San Diego, CA, US as early as possible.

You can expect to pay from £252 to £410 for a bus ticket from Pittsburgh to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £252, which is on 2025-12-14.