Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Salisbury (Citgo Fast Stop) | Gateway Station | CheapestFastest | |||||
Greyhound Lines, Inc. + FlixBus | Salisbury (Citgo Fast Stop) | Gateway Station | No tags |
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Compare 2 ways to travel from Salisbury to St. Louis
Busbud recommends taking the bus from Salisbury to St. LouisAmong the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 21 hours 50 minutes and with fares starting at just US$121, it presents an excellent value for a comfortable ride.
Bus Salisbury, NC, US to St. Louis: Trip Overview
Compare bus companies
Based on 87204 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at US$121
Salisbury to St. Louis Bus
With Busbud, comparing and booking tickets for a bus from Salisbury to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Salisbury to St. Louis will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Salisbury to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Salisbury and St. Louis?
Frequently asked questions on the trip Salisbury, NC, US - St. Louis
How far is St. Louis from Salisbury by coach?
The distance between Salisbury and St. Louis by coach is approximately 573 miles (923 km).
What is the best way to go from Salisbury to St. Louis without flying?
You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to St. Louis was searched and found on 27 Aug 2025 with a price of US$85To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to St. Louis as early as possible.
You can expect to pay from US$85 to US$139 for a bus ticket from Salisbury, NC, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$85, which is on 2025-08-27.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Salisbury to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Salisbury to St. Louis, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Salisbury to St. Louis that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Salisbury to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
What's the cheapest way to go from Salisbury, NC, US to St. Louis?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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