Find coaches from San Diego, CA, US to Buffalo, NY

Previously seen journeys

Next departures from San Diego to Buffalo on 7 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
UCSD Health La Jolla Station
Buffalo (BUF) AirportNo tags
FlixBus + Greyhound
UCSD Health La Jolla Station
Niagara Frontier Transportation AuthorityNo tags
Greyhound
Greyhound Bus Stop
Niagara Frontier Transportation AuthorityNo tags
Greyhound + FlixBus
Greyhound Bus Stop
Buffalo (BUF) AirportNo tags
FlixBus + Greyhound
Greyhound Bus Stop
Buffalo (BUF) AirportNo tags

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Bus San Diego, CA, US to Buffalo, NY: Trip Overview

Average ticket priceUS$266
Average bus trip duration3d 7h
Number of daily buses12
Earliest bus departure06:45
Distance2173 miles
Latest bus departure19:35

San Diego to Buffalo Bus

Busbud helps you find a bus from San Diego to Buffalo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from San Diego to Buffalo will be provided by the most trusted bus companies.

Discover how much the bus trip from San Diego to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Diego, CA, US - Buffalo, NY

  1. How far is Buffalo from San Diego by coach?

    The distance between San Diego and Buffalo by coach is approximately 2181 miles (3518 km).

  2. Is there a way to reach Buffalo from San Diego without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/10
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05/10
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Today
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07/10
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08/10
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09/10
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10/10
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11/10
US$230
busbud logoThe cheapest trip from San Diego, CA, US to Buffalo, NY was searched and found on 11 Oct 2025 with a price of US$230

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Buffalo, NY as early as possible.

You can expect to pay from US$230 to US$230 for a bus ticket from San Diego, CA, US to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at US$230, which is on 2025-10-11.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Diego and Buffalo!

Much more than a mere vehicle taking you from San Diego to Buffalo, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Diego to Buffalo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Diego to Buffalo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to San Diego, CA, US by bus?

Bus from Buffalo, NY to San Diego, CA, US

You can also go to Buffalo, NY by train

Train from San Diego, CA, US to Buffalo, NY

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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