Find coaches from Santander to Brussels

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Compare 2 ways to travel from Santander to Brussels

Bus
Average priceUS$138 - US$171Average duration21h 15m
26kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average priceUS$91 - US$91Average duration14h 20m
43kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Santander to Brussels

Among the sustainable travel choices, the carpool stands out as a good way to reach Brussels. The journey takes about 14 hours 20 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

1carpool per day
14h 20mAverage duration
US$91Cheapest ticket
43kgCO₂ emissions

Bus Santander to Brussels: Trip Overview

Average ticket priceUS$163
Average bus trip duration21h 15m
Number of daily buses4
Earliest bus departure18:35
Distance643 miles

Santander to Brussels Bus

Busbud helps you find a bus from Santander to Brussels. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Santander to Brussels.

From cheap bus tickets to more luxurious buses travelling from Santander to Brussels, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santander - Brussels

  1. How much is the coach fare from Santander to Brussels?

    The prices typically range from US$138 to US$171 on this trip, with the average ticket costing US$163. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long is the coach ride from Santander to Brussels?

    The coach journey between Santander and Brussels lasts about 21h 15m. The fastest coach journey typically takes 19h 5m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time is the first coach from Santander to Brussels?

    The first coach to Brussels from Santander departs at 18:35. Keep in mind that departure times might change on weekends and holidays.

  4. How far is Brussels from Santander by coach?

    The journey from Santander to Brussels by coach covers an approximate distance of 637 miles (1027 km).

  5. What is the best way to go from Santander to Brussels without flying?

    You can choose the coach to travel this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

  6. Is there am overnight bus from Santander to Brussels?

    Yes, you can find coaches leaving until 18:35 and arriving the next day. Make sure to bring a snack and a blanket to keep yourself feeling comfortable during the night.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

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US$154
busbud logoThe cheapest trip from Santander to Brussels was searched and found on 22 May 2025 with a price of US$154

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Brussels as early as possible.

You can expect to pay from US$154 to US$162 for a bus ticket from Santander to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$154, which is on 2025-05-22.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Santander and Brussels!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Santander to Brussels.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santander to Brussels that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santander to Brussels.

Did you know?

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santander by bus?

Bus from Santander to Brussels

Why choose Busbud?

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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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