Find coaches from Wilmington, DE to Charleston, SC, US

Next departures

Next departures from Wilmington to Charleston on 10 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Wilmington Bus Station
4565 Gaynor Ave, North CharlestonCheapest
Greyhound Lines, Inc. + FlixBus
Wilmington Bus Station
4565 Gaynor Ave, North CharlestonFastest
FlixBus
Newark (DE)
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound Lines, Inc.
Newark (DE)
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound Lines, Inc.
Delaware Rest Stop S
4565 Gaynor Ave, North CharlestonNo tags

Last refresh of the prices: Yesterday at 08:26 EDT.

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Compare 2 ways to travel from Wilmington to Charleston

Bus
Average priceUS$52 - US$157Average duration21h 35m
21kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average priceUS$93 - US$284Average duration12h 1m
78kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Wilmington to Charleston

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 12 hours 1 minute and with fares starting at just US$93, it presents an excellent value for a comfortable ride.

2train per day
12h 1mAverage duration
US$93Cheapest ticket
78kgCO₂ emissions

Bus Wilmington, DE to Charleston, SC, US: Trip Overview

Average ticket priceUS$78
Average bus trip duration21h 35m
Number of daily buses6
Earliest bus departure11:20
Distance526 miles
Latest bus departure21:25

Wilmington to Charleston Bus

Busbud helps you find a bus from Wilmington to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Charleston.

Whether it is cheap bus tickets or more luxurious buses going to Charleston from Wilmington, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Wilmington, DE - Charleston, SC, US

  1. How far is Charleston from Wilmington by coach?

    The journey from Wilmington to Charleston by coach covers an approximate distance of 538 miles (868 km).

  2. What is the best way to go from Wilmington to Charleston without flying?

    To travel from Wilmington to Charleston without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07/10
No data
08/10
US$19
Today
US$125
10/10
US$118
11/10
US$89
12/10
US$95
13/10
No data
14/10
No data
busbud logoThe cheapest trip from Wilmington, DE to Charleston, SC, US was searched and found on 8 Oct 2025 with a price of US$19

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Charleston, SC, US as early as possible.

You can expect to pay from US$19 to US$125 for a bus ticket from Wilmington, DE to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$89, which is on 2025-10-11.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Charleston!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Wilmington to Charleston.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Wilmington to Charleston.

Tune out to the fine sounds of your best music playlist on your bus trip from Wilmington to Charleston while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Wilmington, DE to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Wilmington, DE by bus?

Bus from Charleston, SC, US to Wilmington, DE

You can also go to Charleston, SC, US by train

Train from Wilmington, DE to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

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