Bus from Wilmington, DE to Charleston, SC, US: Tickets & Timetables

Next bus departures

Next departures from Wilmington to Charleston on 1 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Newark (DE)
4565 Gaynor Ave, North CharlestonCheapest
Greyhound Lines, Inc.Bus
Wilmington Bus Station
4565 Gaynor Ave, North CharlestonFastest
FlixBus + Greyhound Lines, Inc.
Bus
Delaware Rest Stop S
4565 Gaynor Ave, North CharlestonNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Delaware Rest Stop S
4565 Gaynor Ave, North CharlestonNo tags

Last refresh of the prices: Yesterday at 17:26 EST.

Compare 2 ways to travel from Wilmington to Charleston

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Charleston. The journey takes about 11 hours 39 minutes and with fares starting at just £72, it presents an excellent value for a comfortable ride.

2train per day
11h 39mAverage duration
534 milesDistance
78kgCO₂ emissions
Average price£58 - £199Average duration1d
21kg CO₂e
Average price£72 - £308Average duration11h 39m
78kg CO₂e

Frequently asked questions about travelling by bus from Wilmington, DE to Charleston, SC, US

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Wilmington to Charleston?

    The cheapest coach tickets from Wilmington to Charleston start from £58. The average price for this route is around £83. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Wilmington to Charleston?

    The average bus journey time from Wilmington to Charleston is 1d , covering a distance of 526 miles. The fastest bus can take you there in 20h and is operated by Greyhound.

  3. Which bus companies service the Wilmington to Charleston route?

    Several major bus companies operate on this route with 6 buses available per day, including services from FlixBus, Greyhound.

  4. What is the earliest and latest departure time for the bus from Wilmington to Charleston?

    The earliest bus departs from Wilmington to Charleston at 02:50. And the latest bus departs at 21:25.

  5. What are the CO₂ emissions for the bus trip from Wilmington to Charleston?

    A bus journey from Wilmington to Charleston produces an estimated 21 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

  6. Which is the best bus company from Wilmington to Charleston?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.

  7. Which company has the best Wi-Fi from Wilmington to Charleston?

    Based on Busbud reviews, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company offers the most punctual service from Wilmington to Charleston?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Wilmington to Charleston?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/11
£160
29/11
£105
Today
£200
01/12
£178
02/12
£71
03/12
£64
04/12
£60
05/12
£57
busbud logoThe cheapest trip from Wilmington, DE to Charleston, SC, US was searched and found on 5 Dec 2025 with a price of £57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Charleston, SC, US as early as possible.

You can expect to pay from £57 to £200 for a bus ticket from Wilmington, DE to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at £57, which is on 2025-12-05.

What's the cheapest way to go from Wilmington, DE to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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