Next available departures

Next departures from Buffalo to Syracuse on 18 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags
07:22	Exchange Street Station	2h 27m	09:49	Amtrak Station	No tags

Next departures from Buffalo to Syracuse on 19 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags

Next departures from Buffalo to Syracuse on 20 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags

Next departures from Buffalo to Syracuse on 21 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags
07:22	Exchange Street Station	2h 27m	09:49	Amtrak Station	No tags

Next departures from Buffalo to Syracuse on 22 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags

Next departures from Buffalo to Syracuse on 23 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags

Next departures from Buffalo to Syracuse on 24 April
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
04:45	Depew Station	2h 12m	06:57	Amtrak Station	Cheapest
12:40	Depew Station	2h 4m	14:44	Amtrak Station	Fastest
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
09:05	Depew Station	6h 40m	15:45	SYR Airport	No tags
04:28	Exchange Street Station	2h 29m	06:57	Amtrak Station	No tags

Last refresh of the prices: Today at 14:10 EDT.

Compare 2 ways to travel from Buffalo to Syracuse

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 2 hours 19 minutes and with fares starting at just MAD 277, it presents an excellent value for a comfortable ride.

8train per day

2h 19mAverage duration

134 milesDistance

20kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceMAD 272 - MAD 1,085	Average duration3h 5m	CO₂ emissions 5kg CO₂e
Train	Average priceMAD 277 - MAD 884	Average duration2h 19m	CO₂ emissions 20kg CO₂e

Where are the popular train stations and stops in Buffalo, NY and Syracuse, US?

Buffalo, NY

A
Exchange Street Station
75 Exchange St, Buffalo, NY 14203, USA
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Syracuse, US

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
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Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

15/04

MAD 256

16/04

MAD 303

Today

MAD 550

18/04

MAD 256

19/04

MAD 256

20/04

MAD 256

21/04

MAD 256

22/04

MAD 256

The cheapest trip from Buffalo, NY to Syracuse, US was searched and found on 15 Apr 2026 with a price of MAD 256

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Syracuse, US as early as possible.

You can expect to pay from MAD 256 to MAD 4,260 for a train ticket from Buffalo, NY to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at MAD 256, which is on 2026-04-18.