Find coaches from Boston, MA, US to Greenville, SC

Next bus departures

Next departures from Boston to Greenville on 10 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Boston (South Station)
1116 Woodruff RdCheapest
FlixBus + Greyhound Lines, Inc.
Bus
Brookline
1116 Woodruff RdFastest

Last refresh of the prices: Last Saturday at 9:32 PM EST.

Compare 2 ways to travel from Boston to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 23 hours 5 minutes and with fares starting at just R 1 244, it presents an excellent value for a comfortable ride.

8bus per day
23h 5mAverage duration
1285 kmDistance
32kgCO₂ emissions
Bus
Average priceR 1 244 - R 5 054Average duration23h 5m
32kg CO₂e
Train
Average priceR 3 464 - R 19 602Average duration20h 29m
117kg CO₂e

Frequently asked questions about travelling from Boston, MA, US to Greenville, SC by bus

  1. How much does a bus ticket from Boston to Greenville cost?

    The bus ticket price from Boston to Greenville starts at R 1 244. The best way to find cheap bus tickets from Boston to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Boston to Greenville?

    The average travel time between Boston and Greenville is around 23h 5m, although the fastest bus will take about 20h 20m. This is the time it takes to travel the 1291 km that separates the two cities.

  3. How many daily bus connections are there between Boston and Greenville?

    The number of buses from Boston to Greenville can differ depending on the day of the week. On average, there are 8 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Boston to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Boston to Greenville?

    When taking the bus from Boston to Greenville, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Boston to Greenville?

    Buses travelling between Boston and Greenville leave from Back Bay Station or South Station and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/11
R 2 798
09/11
R 1 778
Today
R 3 045
11/11
R 1 848
12/11
R 1 593
13/11
No data
14/11
R 1 883
15/11
No data
busbud logoThe cheapest trip from Boston, MA, US to Greenville, SC was searched and found on 12 Nov 2025 with a price of R 1 593

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Greenville, SC as early as possible.

You can expect to pay from R 1 593 to R 4 488 for a bus ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 593, which is on 2025-11-12.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Boston, MA, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

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