What is the travel distance from Boston to Greenville?

Boston and Greenville are 801 miles (1291 km) apart.

What are the departure and arrival stations when taking the bus from Boston to Greenville?

The majority of buses traveling from Boston to Greenville start their journey at Back Bay Station and wind up at Guadalajara Supermarket Bus Stop. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

Bus Boston to Greenville from $91 | Refundable Tickets

Next bus departures

Next departures for Boston to Greenville on November 10
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
FlixBus + Greyhound Lines, Inc.	Bus	9:50pm	Boston (South Station)	1d 13h	10:50am	1116 Woodruff Rd	Cheapest
FlixBus + Greyhound Lines, Inc.	Bus	8:55pm	Brookline	1d 10h	7:05am	1116 Woodruff Rd	Fastest

Last refresh of the prices: Last Saturday at 9:32 PM EST.

Compare 2 ways to go from Boston to Greenville

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 23 hours 5 minutes and with fares starting at just $71, it presents an excellent value for a comfortable ride.

8bus per day

23h 5mAverage Duration

797 milesDistance

32kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$71 - $288	Average Duration23h 5m	CO₂ emissions 32kg CO₂e
Train	Average Price$197 - $1,114	Average Duration20h 29m	CO₂ emissions 117kg CO₂e

Compare bus companies

FlixBus

3.5/511,265 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/587,365 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Boston and Greenville?

Stops in Boston

A - Back Bay Station

B - South Station

C - North Station

D - Copley Square

E - Prudential MBTA Station

F - Copley MBTA Station

Stops in Greenville

A - Guadalajara Supermarket Bus Stop

B - Greenville Bus Station

Frequently asked questions about traveling from Boston, MA, US to Greenville, SC by bus

What is the travel distance from Boston to Greenville?
What are the departure and arrival stations when taking the bus from Boston to Greenville?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/08

$159

11/09

$101

Today

$173

11/11

$105

11/12

$91

11/13

No data

11/14

$107

11/15

No data

The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on Nov 12, 2025 with a price of $91

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to Greenville, SC, as early as possible.

You can expect to pay from $91 to $255 for a bus ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-11-12.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.