Find coaches from Pittsburgh to Greenville, SC

Previously seen journeys

Next departures from Pittsburgh to Greenville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    Pittsburgh Intermodal Station
    1116 Woodruff RdNo tags
    Greyhound + FlixBus
      Pittsburgh Intermodal Station
      1116 Woodruff RdNo tags
      Greyhound
        Pittsburgh Intermodal Station
        1116 Woodruff RdNo tags
        Greyhound + FlixBus
          Pittsburgh Intermodal Station
          1116 Woodruff RdNo tags
          Greyhound
            Pittsburgh Intermodal Station
            1116 Woodruff RdNo tags

            Accepted payments

            • Visa
            • MasterCard
            • American Express
            • China Union Pay
            • Diners Club Canada
            • Discover Click to Pay
            • JCB payment
            • Klarna (Pay over time)
            • Google Pay

            Compare 2 ways to travel from Pittsburgh to Greenville

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 5 minutes and with fares starting at just US$99, it presents an excellent value for a comfortable ride.

            3bus per day
            1d Average duration
            657 kmDistance
            16kgCO₂ emissions
            Average priceUS$99 - US$228Average duration1d
            16kg CO₂e
            Average priceUS$193 - US$370Average duration21h 54m
            60kg CO₂e

            Bus Pittsburgh to Greenville, SC: Trip Overview

            Average ticket priceUS$180
            Average bus trip duration1d
            Number of daily buses3
            Earliest bus departure01:30
            Distance657 km
            Latest bus departure21:00

            Pittsburgh to Greenville Bus

            With Busbud, comparing and booking tickets for a bus from Pittsburgh to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Pittsburgh to Greenville.

            Whether it is cheap bus tickets or more luxurious buses going to Greenville from Pittsburgh, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions on the trip Pittsburgh - Greenville, SC

            1. How much does a bus ticket from Pittsburgh to Greenville cost?

              The bus ticket price from Pittsburgh to Greenville starts at US$99. The best way to find cheap bus tickets from Pittsburgh to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Pittsburgh to Greenville?

              The average travel time between Pittsburgh and Greenville is around 1d , although the fastest bus will take about 17h 35m. This is the time it takes to travel the 657 km that separates the two cities.

            3. How many daily bus connections are there between Pittsburgh and Greenville?

              The number of buses from Pittsburgh to Greenville can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Pittsburgh to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Pittsburgh to Greenville?

              When taking the bus from Pittsburgh to Greenville, you can travel comfortably and safely with Greyhound.

            5. What are the departure and arrival stations when taking the bus from Pittsburgh to Greenville?

              Buses travelling between Pittsburgh and Greenville leave from Intermodal Station or Sennott Square and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            29/10
            No data
            30/10
            US$122
            Today
            No data
            01/11
            No data
            02/11
            US$102
            03/11
            No data
            04/11
            No data
            05/11
            No data
            busbud logoThe cheapest trip from Pittsburgh to Greenville, SC was searched and found on 02 Nov 2025 with a price of US$102

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Greenville, SC as early as possible.

            You can expect to pay from US$102 to US$187 for a bus ticket from Pittsburgh to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$102, which is on 2025-11-02.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Pittsburgh to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Pittsburgh to Greenville.

            Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Pittsburgh to Greenville.

            Tune out to the fine sounds of your best music playlist on your bus trip from Pittsburgh to Greenville while indulging in miles on end of beautiful scenic views.

            Did you know?

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

            What's the cheapest way to go from Pittsburgh to Greenville, SC?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Pittsburgh by bus?

            Bus from Greenville, SC to Pittsburgh

            You can also go to Greenville, SC by train

            Train from Pittsburgh to Greenville, SC

            Why choose Busbud?

            The Best Way To Book Bus and Train Tickets

            Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

            People from around the world trust Busbud

            Popular Buses Connecting Pittsburgh

            Buses Leaving from Pittsburgh

            Buses Going to Pittsburgh

            Popular Buses Connecting Greenville

            Buses Leaving from Greenville

            Buses Going to Greenville