Find coaches from Pittsburgh to Greenville, SC

Previously seen journeys

Next departures from Pittsburgh to Greenville on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Pittsburgh Intermodal Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Pittsburgh Intermodal Station
1116 Woodruff RdNo tags
Greyhound
Pittsburgh Intermodal Station
1116 Woodruff RdNo tags
FlixBus + Greyhound
Pittsburgh Intermodal Station
1116 Woodruff RdNo tags
Greyhound
Pittsburgh Intermodal Station
1116 Woodruff RdNo tags

Accepted payments

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Compare 2 ways to travel from Pittsburgh to Greenville

Bus
Average priceUS$68 - US$203Average duration18h 10m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$171 - US$348Average duration21h 54m
60kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Pittsburgh to Greenville

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 18 hours 10 minutes and with fares starting at just US$68, it presents an excellent value for a comfortable ride.

3bus per day
18h 10mAverage duration
US$68Cheapest ticket
16kgCO₂ emissions

Bus Pittsburgh to Greenville, SC: Trip Overview

Average ticket priceUS$87
Average bus trip duration18h 10m
Number of daily buses3
Earliest bus departure00:55
Distance408 miles
Latest bus departure21:00

Pittsburgh to Greenville Bus

With Busbud, comparing and booking tickets for a bus from Pittsburgh to Greenville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Pittsburgh to Greenville.

Whether it is cheap bus tickets or more luxurious buses going to Greenville from Pittsburgh, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Pittsburgh - Greenville, SC

  1. How far is Greenville from Pittsburgh by coach?

    The journey from Pittsburgh to Greenville by coach covers an approximate distance of 408 miles (657 km).

  2. Is there a way to reach Greenville from Pittsburgh without flying?

    To travel from Pittsburgh to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
US$87
12/10
No data
Today
US$80
14/10
No data
15/10
No data
16/10
No data
17/10
No data
18/10
No data
busbud logoThe cheapest trip from Pittsburgh to Greenville, SC was searched and found on 13 Oct 2025 with a price of US$80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Greenville, SC as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Pittsburgh to Greenville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Pittsburgh to Greenville.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Pittsburgh to Greenville.

Tune out to the fine sounds of your best music playlist on your bus trip from Pittsburgh to Greenville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Pittsburgh to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Pittsburgh by bus?

Bus from Greenville, SC to Pittsburgh

You can also go to Greenville, SC by train

Train from Pittsburgh to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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