How much is the bus ticket from Prague to Brussels?

The cheapest coach tickets from Prague to Brussels start from £34. The average price for this route is around £75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus journey from Prague to Brussels?

The average bus journey time from Prague to Brussels is 18h 30m, covering a distance of 447 miles. The fastest bus can take you there in 11h 30m and is operated by FlixBus .

Which bus companies service the Prague to Brussels route?

Several major bus companies operate on this route with 24 buses available per day, including services from FlixBus , BlaBlaCar Bus , RegioJet .

What is the earliest and latest departure time for the bus from Prague to Brussels?

The earliest bus departs from Prague to Brussels at 00:10. And the latest bus departs at 23:05.

What are the CO₂ emissions for the bus trip from Prague to Brussels?

A bus journey from Prague to Brussels produces an estimated 18 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Which is the best bus company from Prague to Brussels?

According to Busbud customers, the highest-rated bus company on this route is RegioJet , with an average rating of 4.1 out of 5 stars based on 1066 reviews.

Which company has the best Wi-Fi from Prague to Brussels?

Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.

Which bus company offers the most punctual service from Prague to Brussels?

According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Prague to Brussels?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet , with a cleanliness rating of 4.4 out of 5 stars.

Bus Prague to Brussels from £32 | Refundable Tickets

Next bus departures

Next departures from Prague to Brussels on 12 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	22:45	PRG Airport	19h 30m	18:15	Brussels North Train Station	Cheapest
Bus	09:50	Prague (Central Bus Station Florenc)	13h 20m	23:10	Brussels North Train Station	Fastest
Bus	04:00	Prague (Main Railway Station)	22h 5m	02:05	Brussels Airport	No tags
Bus	03:50	Prague (Main Station - parking)	20h 50m	00:40	Brussels Airport	No tags
Bus	17:15	Prague (Main Station - parking)	1d 1h	18:40	Brussels Airport	No tags

Next departures from Prague to Brussels on 13 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	09:50	Prague (Central Bus Station Florenc)	13h 20m	23:10	Brussels North Train Station	Cheapest
Bus	18:00	Florenc	12h	06:00	Brussels South (Gare du Midi)	Fastest
Bus	22:00	Prague (Central Bus Station Florenc)	23h 15m	21:15	Brussels Airport	No tags
Bus	04:00	Prague (Main Railway Station)	22h 5m	02:05	Brussels Airport	No tags
Bus	18:45	Prague (Main Railway Station)	1d 2h	21:15	Brussels Airport	No tags

Next departures from Prague to Brussels on 14 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	13:00	Prague (Central Bus Station Florenc)	19h 50m	08:50	Brussels North Train Station	Cheapest
Bus	18:00	Prague (Central Bus Station Florenc)	15h 25m	09:25	Brussels North Train Station	Fastest
Bus	22:00	Prague (Central Bus Station Florenc)	23h 15m	21:15	Brussels Airport	No tags
Bus	18:45	Prague (Main Railway Station)	1d 2h	21:15	Brussels Airport	No tags
Bus	17:30	Prague (Main Station - parking)	1d 7h	00:40	Brussels Airport	No tags

Next departures from Prague to Brussels on 16 January
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	18:00	Florenc	12h	06:00	Brussels South (Gare du Midi)	CheapestFastest

Next departures from Prague to Brussels on 17 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	07:25	Prague (Central Bus Station Florenc)	13h 20m	20:45	Brussels North Train Station	Cheapest
Bus	09:10	Prague (Na Knížecí)	11h 35m	20:45	Brussels North Train Station	Fastest
Bus	16:00	Prague (Central Bus Station Florenc)	17h 25m	09:25	Brussels Airport	No tags
Bus	18:00	Prague (Central Bus Station Florenc)	18h 30m	12:30	Brussels Airport	No tags
Bus	20:00	Prague (Central Bus Station Florenc)	16h 40m	12:40	Brussels Airport	No tags

Last refresh of the prices: Yesterday at 07:08 CET.

Compare 2 ways to travel from Prague to Brussels

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Brussels. The journey takes about 15 hours 25 minutes and with fares starting at just £48, it presents an excellent value for a comfortable ride.

1train per day

15h 25mAverage duration

446 milesDistance

17kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average price£34 - £163	Average duration18h 30m	CO₂ emissions 18kg CO₂e
Train	Average price£48 - £252	Average duration15h 25m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Prague and Brussels?

Stops in Prague

A
Tomíčkova
Tomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Visit page Map
B
Florenc
Křižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
Visit page Map
C
Černý Most
Chlumecká, 198 00 Praha 20, Czech Republic
Visit page Map
D
PRG Airport
Aviatická, 161 08, Praha 6, Czechia
Visit page Map
E
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic
Map
F
Hlavní nádraží
300/8 Wilsonova, 110 00 Praha, Czechia
Visit page Map

Stops in Brussels

A
Brussels South (Gare du Midi)
Rue de France 85, 1060 Saint-Gilles, Belgium
Visit page Map
B
Brux-Nord
Boulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
Visit page Map
C
Congrès
Pachecolaan 5, 1000 Brussel, Belgium
Visit page Map
D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Map

Compare bus companies

FlixBus

3.5/512,006 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

BlaBlaCar Bus

3.5/511,367 reviews

Staff4.4

Timeliness3.7

Cleanliness4.3

WiFi2.6

RegioJet

4/51,066 reviews

Staff4.5

Timeliness3.9

Cleanliness4.4

WiFi3.8

BE bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling by bus from Prague to Brussels

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

How much is the bus ticket from Prague to Brussels?
The cheapest coach tickets from Prague to Brussels start from £34. The average price for this route is around £75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Prague to Brussels?
The average bus journey time from Prague to Brussels is 18h 30m, covering a distance of 447 miles. The fastest bus can take you there in 11h 30m and is operated by FlixBus.
Which bus companies service the Prague to Brussels route?
Several major bus companies operate on this route with 24 buses available per day, including services from FlixBus, BlaBlaCar Bus, RegioJet.
What is the earliest and latest departure time for the bus from Prague to Brussels?
The earliest bus departs from Prague to Brussels at 00:10. And the latest bus departs at 23:05.
What are the CO₂ emissions for the bus trip from Prague to Brussels?
A bus journey from Prague to Brussels produces an estimated 18 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Prague to Brussels?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1066 reviews.
Which company has the best Wi-Fi from Prague to Brussels?
Based on Busbud reviews, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company offers the most punctual service from Prague to Brussels?
According to Busbud traveller reviews, the most punctual bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Prague to Brussels?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.4 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/01

£53

11/01

£50

Today

£47

13/01

£34

14/01

£38

15/01

No data

16/01

£37

17/01

£37

The cheapest trip from Prague to Brussels was searched and found on 13 Jan 2026 with a price of £34

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

You can expect to pay from £34 to £88 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at £34, which is on 2026-01-13.