Find coaches from Prague to Brussels

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Sat31 May
Today1 Jun
from US$77
Tomorrow2 Jun
Tue3 Jun
from US$61
Wed4 Jun
from US$50
Thu5 Jun
Fri6 Jun
Sat7 Jun

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 1 June at
    Departure city: Prague
    Departure location: PRG Airport
    Arrival time: 2 June at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 1 June at
    Departure city: Prague
    Departure location: Prague (Na Knížecí)
    Arrival time: 1 June at
    Destination city: Brussels
    Destination location: Brussels-North (Gare du Nord)
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: 1 June at
    Departure city: Prague
    Departure location: Florenc
    Arrival time: 2 June at
    Destination city: Brussels
    Destination location: Brussels North Train Station
    Operated by: BlaBlaCar BusBlaBlaCar Bus
    Vehicle: BusDuration:
  • Departure time: 1 June at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: 2 June at
    Destination city: Brussels
    Destination location: Brussels Airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:
  • Departure time: 1 June at
    Departure city: Prague
    Departure location: Prague (Central Bus Station Florenc)
    Arrival time: 2 June at
    Destination city: Brussels
    Destination location: Brussels Airport
    Operated by: FlixbusFlixbus
    Vehicle: BusDuration:

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Compare 2 ways to travel from Prague to Brussels

Bus
Average priceUS$40 - US$199Average duration18h 25m
18kg CO₂e5 out of 5 stars
Cheapest
Train
Average priceUS$113 - US$373Average duration13h 10m
17kg CO₂e5 out of 5 stars
FastestMost eco-friendly
busbud logoBusbud recommends taking the bus from Prague to Brussels

Among the sustainable travel choices, the bus stands out as a good way to reach Brussels. The journey takes about 18 hours 25 minutes and with fares starting at just US$40, it presents an excellent value for a comfortable ride.

13bus per day
18h 25mAverage duration
US$40Cheapest ticket
18kgCO₂ emissions

Bus Prague to Brussels: Trip Overview

Average ticket priceUS$83
Average bus trip duration18h 25m
Number of daily buses13
Earliest bus departure00:10
Distance440 miles
Latest bus departure23:05

Prague to Brussels Bus

With Busbud, comparing and booking tickets for a bus from Prague to Brussels is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Prague to Brussels from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Brussels from Prague, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Prague - Brussels

  1. How much is the coach fare from Prague to Brussels?

    Coach ticket prices from Prague to Brussels can start as low as US$40, though the average price for this trip is US$83. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. Keep in mind that booking tickets on the day of travel might result in higher prices.

  2. How long is the coach ride from Prague to Brussels?

    The coach journey between Prague and Brussels lasts about 18h 25m. If you're looking for the fastest trip, you can get there in just about 12h. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from Prague to Brussels?

    The first coach from Prague to Brussels leaves at 00:10. Times and services may vary during weekends and holidays.

  4. How far is Brussels from Prague by coach?

    The journey from Prague to Brussels by coach covers an approximate distance of 446 miles (719 km).

  5. What is the best way to go from Prague to Brussels without flying?

    To travel from Prague to Brussels without flying, you can take the coaches. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/05
US$60
31/05
US$186
Today
US$72
02/06
US$36
03/06
US$58
04/06
US$46
05/06
US$147
06/06
US$58
busbud logoThe cheapest trip from Prague to Brussels was searched and found on 2 Jun 2025 with a price of US$36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Brussels as early as possible.

You can expect to pay from US$36 to US$228 for a bus ticket from Prague to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at US$36, which is on 2025-06-02.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Prague to Brussels.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Prague to Brussels, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Prague to Brussels.

Make a music playlist for your bus ride from Prague to Brussels, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Prague to Brussels?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Prague by bus?

Bus from Prague to Brussels

You can also go to Brussels by train

Train from Prague to Brussels

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

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