Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal Barrancas de San Antonio | Terminal San Borja | Cheapest | |||||
| Terminal Barrancas de San Antonio | Santiago (Terminal Del Sol) | Fastest | |||||
| Terminal Barrancas de San Antonio | Terminal San Borja | No tags | |||||
| Terminal Barrancas de San Antonio | Terminal San Borja | No tags | |||||
| Terminal Barrancas de San Antonio | Terminal San Borja | No tags |
Last refresh of the prices: Today at 11:01 AM -03.
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Get from San Antonio to Santiago
This route is served by bus onlyThe journey takes about 1 hour 40 minutes, and with fares starting at just US$5, it presents an excellent value for a comfortable ride.
Bus San Antonio, CL to Santiago, CL: Trip Overview
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Based on 11120 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at US$5
San Antonio to Santiago Bus
With Busbud, comparing and booking tickets for a bus from San Antonio to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from San Antonio to Santiago will be provided by the most trusted bus companies.
Discover how much the bus trip from San Antonio to Santiago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in San Antonio and Santiago?
Frequently asked questions on the trip San Antonio, CL - Santiago, CL
How much does a bus ticket from San Antonio to Santiago cost?
The bus ticket price from San Antonio to Santiago starts at US$5. The best way to find cheap bus tickets from San Antonio to Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from San Antonio to Santiago?
The average travel time between San Antonio and Santiago is around 1h 40m, although the fastest bus will take about 1h 20m. This is the time it takes to travel the 99 km that separates the two cities.
How many daily bus connections are there between San Antonio and Santiago?
The number of buses from San Antonio to Santiago can differ depending on the day of the week. On average, there are 24 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from San Antonio to Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from San Antonio to Santiago?
When taking the bus from San Antonio to Santiago, you can travel comfortably and safely with FlixBus.
What are the departure and arrival stations when taking the bus from San Antonio to Santiago?
Buses travelling between San Antonio and Santiago leave from Terminal Barrancas de San Antonio or San Antonio and arrive at Terminal Sur, San Borja, Terminal Los Héroes.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, CL to Santiago, CL was searched and found on 30 Oct 2025 with a price of US$4To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, CL to Santiago, CL as early as possible.
You can expect to pay from US$4 to US$10 for a bus ticket from San Antonio, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$4, which is on 2025-11-04.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from San Antonio to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from San Antonio to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Antonio to Santiago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from San Antonio to Santiago while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Top travelled bus routes
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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
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Popular Buses Connecting San Antonio
Buses Leaving from San Antonio
Buses Going to San Antonio
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Puerto Montt
- Coach Santiago - Concepción
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- Bus from Santiago to La Serena
- Coach Santiago - Temuco
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- Coach Santiago - Parral
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- Coach Santiago - Lanco
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- Bus from Santiago to Litueche
- Coach Santiago - Pinto
- Bus Santiago - Quirihue
Buses Going to Santiago
- Bus from Victoria to Santiago
- Coach Concepción - Santiago
- Bus Castro - Santiago
- Bus from Valdivia to Santiago
- Coach Mendoza - Santiago
- Bus Antofagasta - Santiago
- Bus from Lago Ranco to Santiago
- Coach Cholchol - Santiago
- Bus Chiguayante - Santiago
- Bus from Taltal to Santiago
- Coach Bulnes - Santiago
- Bus Parral - Santiago
- Bus from Teodoro Schmidt to Santiago
- Coach Melipeuco - Santiago
- Bus Talcahuano - Santiago