Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Barrancas de San Antonio | Terminal San Borja | Cheapest | ||||
| Bus | Terminal Barrancas de San Antonio | Santiago (Terminal Del Sol) | Fastest | ||||
| Bus | Terminal Barrancas de San Antonio | Terminal San Borja | No tags | ||||
| Bus | Terminal Barrancas de San Antonio | Terminal San Borja | No tags | ||||
| Bus | Terminal Barrancas de San Antonio | Terminal San Borja | No tags |
Last refresh of the prices: Yesterday at 10:46 AM -03.
Get from San Antonio to Santiago
The journey takes about 1 hour 40 minutes, and with fares starting at just $7, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 11359 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $7
Where are the popular stops in San Antonio and Santiago?
Frequently asked questions about travelling from San Antonio, CL to Santiago, CL by bus
What is the distance between San Antonio and Santiago?
The distance between San Antonio and Santiago is approximately 99 km (61 miles).
What are the departure and arrival locations for buses traveling from San Antonio to Santiago?
Buses departing from Terminal Barrancas de San Antonio in San Antonio will take you to Terminal Sur in Santiago.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, CL to Santiago, CL was searched and found on Nov 19, 2025 with a price of $6To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, CL to Santiago, CL, as early as possible.
You can expect to pay from $6 to $13 for a bus ticket from San Antonio, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $6 which is on 2025-11-19.
Top travelled bus routes
People from around the world trust Busbud
Popular Buses Connecting San Antonio
Buses Leaving from San Antonio
- Bus from San Antonio to Temuco
- Bus San Antonio - Talca
- San Antonio - Santiago
- Bus from San Antonio to Puerto Varas
- Bus San Antonio - La Serena
- San Antonio - Valparaiso
- Bus from San Antonio to Chillan
- Bus San Antonio - Coquimbo
- San Antonio - Puerto Montt
- Bus from San Antonio to Vina del Mar
- Bus San Antonio - Pucon
Buses Going to San Antonio
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Temuco
- Bus Santiago - La Serena
- Santiago - Mendoza
- Bus from Santiago to Chillan
- Bus Santiago - Talca
- Santiago - Valdivia
- Bus from Santiago to Coquimbo
- Bus Santiago - Pichilemu
- Santiago - Lolol
- Bus from Santiago to Iquique
- Bus Santiago - Copiapo
- Santiago - Caldera
- Bus from Santiago to San Antonio
- Bus Santiago - Los Andes
- Santiago - Cherquenco
Buses Going to Santiago
- Bus from Victoria to Santiago
- Bus Concepción - Santiago
- Castro - Santiago
- Bus from San Felipe to Santiago
- Bus Antofagasta - Santiago
- Quintero - Santiago
- Bus from Coquimbo to Santiago
- Bus Los Lagos - Santiago
- Vina del Mar - Santiago
- Bus from San Antonio to Santiago
- Bus Puerto Montt - Santiago
- Pichilemu - Santiago
- Bus from Galvarino to Santiago
- Bus Iquique - Santiago
- San Pedro de la Paz - Santiago
Popular routes in this country
- Bus from Castro to Ancud
- Bus Puerto Varas - Castro
- Santiago - Pucon
- Bus from Santiago to Valparaiso
- Bus Calama - Santiago
- Santiago - Vina del Mar
- Bus from Puerto Natales to Estancia Pudeto
- Bus Puerto Montt - Pucon
- Calama - Arica Province
- Bus from Ancud to Puerto Montt
- Bus Arica Province - Calama
- Temuco - Pucon
- Bus from Valdivia to Santiago
- Bus Santiago - Antofagasta
- Pucon - Santiago