Find coaches from San Antonio (Valparaiso Region), CL to Santiago, CL

Find affordable coach tickets from San Antonio (Valparaiso Region), CL to Santiago, CL with flexible options. Book your journey now

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Mon16 Jun
from US$6
Tue17 Jun
Wed18 Jun
Thu19 Jun
Fri20 Jun
Sat21 Jun
from US$7
Sun22 Jun
Mon23 Jun

Cheap buses leaving Saturday

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 21 June at
    Departure city: San Antonio
    Departure location: Terminal Barrancas de San Antonio
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal San Borja
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 21 June at
    Departure city: San Antonio
    Departure location: Terminal Barrancas de San Antonio
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal San Borja
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: San Antonio
    Departure location: Terminal Barrancas de San Antonio
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal San Borja
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: San Antonio
    Departure location: Terminal Barrancas de San Antonio
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal San Borja
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:
  • Departure time: 21 June at
    Departure city: San Antonio
    Departure location: Terminal Barrancas de San Antonio
    Arrival time: 21 June at
    Destination city: Santiago
    Destination location: Terminal San Borja
    Operated by: Flixbus ChileFlixbus Chile
    Vehicle: BusDuration:

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Bus San Antonio to Santiago: Trip Overview

Average ticket priceUS$6
Average bus trip duration1h 45m
Number of daily buses21
Earliest bus departure06:00
Distance55 miles
Latest bus departure20:30

San Antonio to Santiago Bus

With Busbud, comparing and booking tickets for a bus from San Antonio to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from San Antonio to Santiago will be provided by the most trusted bus companies.

Discover how much the bus trip from San Antonio to Santiago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Antonio (Valparaiso Region), CL - Santiago, CL

  1. How much does it cost to go to Santiago by bus?

    Coach ticket prices from San Antonio to Santiago can start as low as US$3, though the average price for this trip is US$6. The actual price may differ based on factors like the time you plan to travel, the day of the week, and the coach service provider you select. Keep in mind that booking tickets on the day of travel might result in higher prices.

  2. How long is a coach from San Antonio to Santiago?

    The coach journey between San Antonio and Santiago lasts about 1h 45m. The quickest coach journey typically takes 1h 40m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time is the first coach from San Antonio to Santiago?

    The first coach from San Antonio to Santiago leaves at 06:00. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between San Antonio and Santiago by coach?

    The journey from San Antonio to Santiago by coach covers an approximate distance of 61 miles (99 km).

  5. What is the best way to go from San Antonio to Santiago without a car?

    You can reach Santiago from San Antonio by coach, as there are regular services between the two locations. Depending on your preferences, carpooling can also be considered as an option.

  6. Can you go on a day trip from San Antonio to Santiago?

    Absolutely, a day trip from San Antonio to Santiago is totally possible. It takes about 3h 20m in total to complete a round-trip between the two locations. This means you'll have plenty of time to enjoy the day in Santiago before returning.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/06
US$6
13/06
US$6
Today
US$6
15/06
US$6
16/06
US$6
17/06
US$3
18/06
US$3
19/06
US$3
busbud logoThe cheapest trip from San Antonio to Santiago was searched and found on 17 Jun 2025 with a price of US$3

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio to Santiago as early as possible.

You can expect to pay from US$3 to US$7 for a bus ticket from San Antonio to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at US$3, which is on 2025-06-17.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Antonio to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from San Antonio to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Antonio to Santiago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from San Antonio to Santiago while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to San Antonio by bus?

Bus from San Antonio to Santiago

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