- Santa Bárbara to Santiago buses
 
Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link | 
|---|---|---|---|---|---|---|---|---|
![]()  | Santa Bárbara | Terminal Sur | CheapestFastest | |||||
![]()  | Santa Bárbara | Terminal Sur | No tags | 
Last refresh of the prices: 10/28/2025 -03.
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Get from Santa Bárbara to Santiago
The journey takes about 5 hours 53 minutes, and with fares starting at just R 237, it presents an excellent value for a comfortable ride.
Bus Santa Bárbara, CL to Santiago, CL: Trip Overview
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Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the Wi-Fi. Eme Bus ticket prices on this trip start at R 237
Santa Bárbara to Santiago Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Bárbara to Santiago.
Bus service from Santa Bárbara to Santiago will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Santa Bárbara to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Santa Bárbara and Santiago?
Frequently asked questions on the trip Santa Bárbara, CL - Santiago, CL
How much does a bus ticket from Santa Bárbara to Santiago cost?
The bus ticket price from Santa Bárbara to Santiago starts at R 237. The best way to find cheap bus tickets from Santa Bárbara to Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Santa Bárbara to Santiago?
The average travel time between Santa Bárbara and Santiago is around 5h 53m, although the fastest bus will take about 5h 53m. This is the time it takes to travel the 490 km that separates the two cities.
How many daily bus connections are there between Santa Bárbara and Santiago?
The number of buses from Santa Bárbara to Santiago can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Bárbara to Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Santa Bárbara to Santiago?
When taking the bus from Santa Bárbara to Santiago, you can travel comfortably and safely with Eme Bus.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Bárbara, CL to Santiago, CL as early as possible.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Bárbara to Santiago but it'll also be endearing to native speakers who will surely appreciate your effort.
Much more than a mere vehicle taking you from Santa Bárbara to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Bárbara to Santiago that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Bárbara to Santiago.
Did you know?
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Top travelled bus routes
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Popular Buses Connecting Santa Bárbara
Buses Leaving from Santa Bárbara
Buses Going to Santa Bárbara
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Concepción
 - Coach Santiago - Puerto Montt
 - Bus Santiago - Antofagasta
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 - Coach Santiago - Temuco
 - Bus Santiago - Mendoza
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 - Coach Santiago - Chimbarongo
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 - Coach Santiago - Calbuco
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 - Coach Santiago - Marchigüe
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Buses Going to Santiago
- Bus from Victoria to Santiago
 - Coach Concepción - Santiago
 - Bus Mendoza - Santiago
 - Bus from Castro to Santiago
 - Coach Valdivia - Santiago
 - Bus Antofagasta - Santiago
 - Bus from Curacautín to Santiago
 - Coach Pullalli - Santiago
 - Bus Polcura - Santiago
 - Bus from Pucon to Santiago
 - Coach Hualqui - Santiago
 - Bus Mehuin - Santiago
 - Bus from Caldera to Santiago
 - Coach Arica Province - Santiago
 - Bus San Ignacio - Santiago
 



