Based on 85 reviews, the company was rated 3.9 stars on Busbud. Travellers were especially satisfied with the departure location and the seats but often complained with the Wi-Fi. Pluss Chile ticket prices on this trip start at R 169
Based on 11535 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the Wi-Fi. FlixBus ticket prices on this trip start at R 148
Based on 127 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the staff and the ticket access but often complained with the Wi-Fi. Cikbus Elité ticket prices on this trip start at R 153
Cikbus Elité / Ciktur Santiago La Serena recent customer reviews
Timely service, arrived a little early at destination. Comfortable, but the seat my partner had would not stay upright, it would slowly recline.
4 out of 5 stars
Nigel P.
The best company I have ever seen. Really comfortable seats and pillows. I have problems with sleeping in buses but now I had decent rest. I recommend
Based on 55 reviews, the company was rated 4.2 stars on Busbud. Travellers were especially satisfied with the ticket access and the seats but often complained with the Wi-Fi. Buses Andimar ticket prices on this trip start at R 189
Andimar Santiago La Serena recent customer reviews
We actually rebooked to Flixbus. We felt very safe two drivers and supported by a third person. Very properly! Nice service!
Based on 52 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the Wi-Fi. Buses Romani ticket prices on this trip start at R 163
Based on 13 reviews, the company was rated 3.6 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained with the timeliness. Pullman San Andres ticket prices on this trip start at R 251
According to 12 reviews, Buses Paravias received a 2.6-star rating for this journey. Travellers were especially satisfied with the staff and the seats, but some complained about the temperature. Buses Paravias ticket prices on this trip start at R 185
Buses Paravias Santiago La Serena recent customer reviews
Bus showed up an hour late without functioning AC. An hour into the trip the bus broke down and we had to wait two hours for a replacement, we were a total of 4 hours late to our destination. Never again.
1 out of 5 stars
Marco André A.
my bus was canceled, there was no information about it, I did not get refund for the ticket
1 out of 5 stars
Stefano S.
The bus really smelt of toilet and the air conditioner was broken. There was a window that the staff were not happy for us to open.
Based on 12 reviews, Serena Mar was rated 4 stars for this trip. Serena Mar ticket prices on this trip start at R 249, with the trip lasting on average 375.
Serena Mar Santiago La Serena recent customer reviews
While we were riding, there were an odd series of noises, noises that I presume were the audio of a film, coming from the speakers above the seats. The noises were quite annoying and went on for some time before the attendant came to stop them.
3 out of 5 stars
Matthew O.
It was a bit dirty
2 out of 5 stars
Andre C.
Toilet didn't work fully, but was a comfortable ride. All in all good!
Buses Evans offers 1 daily departures, and you can find tickets starting at R 824. The quickest ride takes around 420. Buses Evans offers a cost-effective solution to get you where you need to be.
Based on 19 reviews, Condor Bus was rated 3.6 stars for this trip. Condor Bus ticket prices on this trip start at R 257, with the trip lasting on average 418.
Based on 3 reviews, the company was rated 4.3 stars on Busbud. Travellers were especially satisfied with the staff and the timeliness but often complained with the Wi-Fi. Clikbus ticket prices on this trip start at R 268
Frequently asked questions about travelling from Santiago, CL to La Serena, CL by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Santiago to La Serena?
The cheapest bus tickets from Santiago to La Serena start at R 148. The average price for this route is around R 319. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Santiago to La Serena?
The average bus journey time from Santiago to La Serena is 6h 20m, covering a distance of 399 km. The fastest bus gets you there in 5h 30m and is operated by Serena Mar.
Which bus companies service the Santiago to La Serena route?
What is the earliest and latest departure time for the bus from Santiago to La Serena?
The earliest bus departs from Santiago to La Serena at 06:15. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Santiago to La Serena?
A bus trip from Santiago to La Serena produces an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Santiago to La Serena?
According to Busbud customers, the highest-rated bus company on this route is Clikbus, with an average rating of 4.3 out of 5 stars based on 3 reviews.
Which bus company has the best Wi-Fi from Santiago to La Serena?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Santiago to La Serena?
According to Busbud traveller reviews, the most punctual bus company on this route is Clikbus, with a punctuality rating of 5.0 out of 5 stars.
Which bus company has the cleanest buses from Santiago to La Serena?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Buses Andimar, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
04/12
R 248
05/12
R 367
Today
R 232
07/12
R 174
08/12
R 248
09/12
R 174
10/12
R 175
11/12
R 174
The cheapest trip from Santiago, CL to La Serena, CL was searched and found on 07 Dec 2025 with a price of R 174
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santiago, CL to La Serena, CL as early as possible.
You can expect to pay from R 174 to R 700 for a bus ticket from Santiago, CL to La Serena, CL based on the last 2 days. You can expect to find the cheapest price for the trip at R 174, which is on 2025-12-07.
Usually Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from Santiago, CL to La Serena, CL was searched and found on 07 Dec 2025 with a price of R 174
