Bus Tickets from Santa Bárbara (Biobio Region), CL to Santiago, CL

Find affordable bus tickets from Santa Bárbara (Biobio Region), CL to Santiago, CL with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Santa Bárbara to Santiago: Trip Overview

Average Ticket PriceUS$15
Average Bus Trip Duration5h 53m
Number of daily buses2
Earliest bus departure5:50am
Distance483 km
Latest bus departure9:50pm

Santa Bárbara to Santiago Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Bárbara to Santiago.

Bus service from Santa Bárbara to Santiago will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from Santa Bárbara to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Bárbara (Biobio Region), CL - Santiago, CL

  1. How long is the bus ride from Santa Bárbara to Santiago?

    The trip from Santa Bárbara to Santiago will take on average 5h 53m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 5h 53m.

  2. How far is Santa Bárbara from Santiago?

    The distance between Santa Bárbara and Santiago is approximately 490 km (304 miles).

  3. What are the departure and arrival locations for buses traveling from Santa Bárbara to Santiago?

    Buses departing from Terminal Buses Aranguiz de Santa Bárbara in Santa Bárbara will take you to Terminal Sur in Santiago.

  4. What is the cheapest way to get from Santa Bárbara to Santiago?

    If you're on a budget, consider traveling by bus to Santiago from Santa Bárbara; it tends to be more affordable. With a starting ticket price of US$14, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Santa Bárbara to Santiago?

    The bus from Santa Bárbara to Santiago will cost you US$15, on average.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-04
US$13
06-05
No data
Today
US$14
06-07
No data
06-08
No data
06-09
No data
06-10
No data
06-11
No data
busbud logoThe cheapest trip from Santa Bárbara to Santiago was searched and found on Jun 4, 2025 with a price of US$13

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Bárbara to Santiago, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Bárbara to Santiago but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Santa Bárbara to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Bárbara to Santiago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Santa Bárbara to Santiago.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Santa Bárbara by bus?

Bus from Santa Bárbara to Santiago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Santa Bárbara

Buses Leaving from Santa Bárbara

Buses Going to Santa Bárbara

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago