Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Santa Bárbara | Terminal Sur | Cheapest | ||||
| Bus | Santa Bárbara | Terminal Sur | Fastest | ||||
| Bus | Santa Bárbara | Terminal Sur | No tags | ||||
| Bus | Santa Bárbara | Terminal Sur | No tags | ||||
| Bus | Santa Bárbara | Terminal Sur | No tags |
Last refresh of the prices: Last Tuesday at 11:14 AM -03.
Get from Santa Bárbara to Santiago
The journey takes about 5 hours 53 minutes, and with fares starting at just $20, it presents an excellent value for a comfortable ride.
Where are the popular stops in Santa Bárbara and Santiago?
Stops in Santa Bárbara
- A
Terminal Buses Aranguiz de Santa Bárbara
Baquedano 999, Santa Bárbara, Región del Bío Bío, Chile
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Zapadores
Los Zapadores 608, Recoleta, Región Metropolitana, Chile
Compare bus companies
Based on 157 reviews, the company was rated 3.8 stars on Busbud. Travellers were especially satisfied with the cleanliness and the ticket access but often complained with the WiFi. Eme Bus ticket prices on this trip start at $20
Frequently asked questions about travelling from Santa Bárbara, CL to Santiago, CL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Santa Bárbara to Santiago?
The cheapest bus tickets from Santa Bárbara to Santiago start from $20. The average price for this route is around $22. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Santa Bárbara to Santiago?
The average bus travel time from Santa Bárbara to Santiago is 5h 53m, covering a distance of 484 km. The quickest bus can get you there in 5h 53m and is operated by Eme Bus.
Which bus companies service the Santa Bárbara to Santiago route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Santa Bárbara to Santiago?
The earliest bus departs from Santa Bárbara to Santiago at 5:50am. And the latest bus departs at 9:50pm.
What are the CO₂ emissions for the bus trip from Santa Bárbara to Santiago?
A bus trip from Santa Bárbara to Santiago generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Santa Bárbara, CL to Santiago, CL was searched and found on Dec 7, 2025 with a price of $25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Bárbara, CL to Santiago, CL, as early as possible.
You can expect to pay from $25 to $42 for a bus ticket from Santa Bárbara, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2025-12-07.
