Next departures for Ann Arbor to Syracuse on November 20
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Departure time
Departure location
Trip duration
Arrival time
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Price and booking link
Bus
Ann Arbor
Syracuse (Regional Transportation Center)
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Bus
Ann Arbor
Syracuse (Regional Transportation Center)
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Bus
Ann Arbor
Syracuse (Regional Transportation Center)
No tags
Bus
Ann Arbor
Syracuse (Regional Transportation Center)
No tags
Bus
Ann Arbor
Syracuse (Regional Transportation Center)
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Compare 2 ways to go from Ann Arbor to Syracuse
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 20 hours 30 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.
Based on 5594 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $101
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210Syracuse University
D - Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E - New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F - Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Frequently asked questions about traveling from Ann Arbor to Syracuse, US by bus
What is the travel distance from Ann Arbor to Syracuse?
The distance between the two cities is 389 miles (628 km).
What are the departure and arrival stations when taking the bus from Ann Arbor to Syracuse?
The majority of buses traveling from Ann Arbor to Syracuse start their journey at Train Station and wind up at Regional Transportation Center. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Syracuse?
Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Central New York Playhouse, Webster Pond, The Great New York State Fair, Rosamond Gifford Zoo and The Fun Warehouse.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
No data
11/19
$110
Today
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11/21
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11/22
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11/23
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11/24
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11/25
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The cheapest trip from Ann Arbor to Syracuse, US was searched and found on Nov 19, 2025 with a price of $110
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ann Arbor to Syracuse, US, as early as possible.
What's the cheapest way to go from Ann Arbor to Syracuse, US?
The bus is the cheapest travel choice for this destination