Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Des Moines | Glendale Bus Stop | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Des Moines | Phoenix Airport (PHX)/44th Street station | No tags |
Last refresh of the prices: Yesterday at 7:48 AM CST.
Get from Des Moines to Phoenix
The journey takes about 1 day, 23 hours 55 minutes and with fares starting at just $160, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Phoenix?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Phoenix
- A1614 N 27th Ave, Phoenix, AZ 85009, USA
- B
Phoenix Greyhound Station
2115 E Buckeye Rd, Phoenix, AZ 85034, USA - C
Glendale Ave
2647 W Glendale Ave, Ste 17, Phoenix, Az, Glendale, AZ 85051 - D
44th St Stn
44th Street Transit Center 42009 E Washigton Street, 85034 - E
Desert Ridge
Mellow Mushroom, 5293-5343 E Deer Valley Dr, Phoenix, AZ 85054, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Des Moines to Phoenix, AZ by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Phoenix?
The cheapest bus tickets from Des Moines to Phoenix start from $160. The average price for this route is around $212. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Phoenix?
The average bus trip duration from Des Moines to Phoenix is 1d 23h, covering a distance of 1155 miles (1863 km). The quickest bus can get you there in 1d 22h and is operated by Greyhound.
Which bus companies service the Des Moines to Phoenix route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Des Moines to Phoenix?
The earliest bus departs from Des Moines to Phoenix at 7:15pm. And the latest bus departs at 7:15pm.
What are the CO₂ emissions for the bus trip from Des Moines to Phoenix?
A bus trip from Des Moines to Phoenix generates an estimated 47 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Phoenix, AZ was searched and found on Mar 1, 2026 with a price of $192To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Phoenix, AZ, as early as possible.
You can expect to pay from $192 to $450 for a bus ticket from Des Moines to Phoenix, AZ based on the last 2 days. You can expect to find the cheapest price for the trip at $192 which is on 2026-03-01.
