Bus Tickets from Frederick to Panama City, US

Frequently asked questions for your trip Frederick - Panama City, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/04
$158
10/05
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Today
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10/07
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10/08
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10/09
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busbud logoThe cheapest trip from Frederick to Panama City, US was searched and found on Oct 4, 2025 with a price of $158

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frederick to Panama City, US, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Frederick to Panama City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Frederick to Panama City.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Frederick to Panama City that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Frederick to Panama City, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Frederick by bus?

Bus from Panama City, US to Frederick

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