Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminál | Hotelu Grand | Cheapest | ||||
| Bus | Terminál | Hotelu Grand | Fastest | ||||
 | Bus | Terminál | Hotelu Grand | No tags | ||||
| Bus | Terminál | Hotelu Grand | No tags | ||||
| Bus | Terminál | Hotelu Grand | No tags |
Last refresh of the prices: Yesterday at 3:47 PM CET.
Get from Karlovy Vary to Brno
The journey takes about 5 hours 55 minutes and with fares starting at just $14, it presents an excellent value for a comfortable ride.
Where are the popular stops in Karlovy Vary and Brno?
Stops in Karlovy Vary
- AZápadní 2080/2A, 360 01 Karlovy Vary, Czech Republic
- B
Tržnice
Varšavská 1275/5, 360 01 Karlovy Vary, Czech Republic
Stops in Brno
- ABenešova 603/2, Brno-město, 602 00 Brno-Brno-střed, Czech Republic
- BZvonařka 411, Trnitá, 602 00 Brno-Brno-střed, Czech Republic
- CNádražní 418/1, Brno-město, 602 00 Brno-Brno-střed, Czechia
- DBrno Bus Station, ÚAN Zvonařka, 602 00 Brno-střed, Czechia
- E
Ústřední hřbitov
Vídeňská 306/94, Štýřice, 639 00 Brno-Brno-střed, Czechia - F
Vídeňská 98
Vídeňská 98, 619 00 Brno-jih, Czechia
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Frequently asked questions about traveling from Karlovy Vary to Brno by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Karlovy Vary to Brno?
The cheapest bus tickets from Karlovy Vary to Brno start from $14. The average price for this route is around $26. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Karlovy Vary to Brno?
The average bus trip duration from Karlovy Vary to Brno is 5h 55m, covering a distance of 182 miles (294 km). The quickest bus can get you there in 5h 10m and is operated by FlixBus.
Which bus companies service the Karlovy Vary to Brno route?
What is the earliest and latest departure time for the bus from Karlovy Vary to Brno?
The earliest bus departs from Karlovy Vary to Brno at 6:00am. And the latest bus departs at 8:30pm.
What are the CO₂ emissions for the bus trip from Karlovy Vary to Brno?
A bus trip from Karlovy Vary to Brno generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Karlovy Vary to Brno?
According to Busbud customers, the highest-rated bus company on this route is RegioJet, with an average rating of 4.1 out of 5 stars based on 1057 reviews.
Which bus company has the best Wi-Fi from Karlovy Vary to Brno?
Based on reviews on Busbud, the bus company RegioJet has the best Wi-Fi rating with a score of 3.8.
Which bus company has the most timely service from Karlovy Vary to Brno?
According to Busbud traveller reviews, the most timely bus company on this route is RegioJet, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Karlovy Vary to Brno?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is RegioJet, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Karlovy Vary to Brno was searched and found on Nov 27, 2025 with a price of $11To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlovy Vary to Brno, as early as possible.
You can expect to pay from $11 to $36 for a bus ticket from Karlovy Vary to Brno based on the last 2 days. You can expect to find the cheapest price for the trip at $18 which is on 2025-12-02.
